|Application ||WB, IHC-P, FC, E|
|Calculated MW||21850 Da|
|Antigen Region||156-184 aa|
|Other Names||U3 small nucleolar ribonucleoprotein protein IMP3, U3 snoRNP protein IMP3, BRMS2, IMP3, C15orf12, MRPS4|
|Target/Specificity||This IMP3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 156-184 amino acids from the C-terminal region of human IMP3.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||IMP3 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Component of the 60-80S U3 small nucleolar ribonucleoprotein (U3 snoRNP). Required for the early cleavages during pre-18S ribosomal RNA processing.|
|Cellular Location||Nucleus, nucleolus|
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Provided below are standard protocols that you may find useful for product applications.
This gene encodes the human homolog of the yeast Imp3 protein. The protein localizes to the nucleoli and interacts with the U3 snoRNP complex. The protein contains an S4 domain.
Li, D., et al. Ann. Surg. Oncol. 16(12):3499-3506(2009) Walter, O., et al. Hum. Pathol. 40(11):1528-1533(2009) Riener, M.O., et al. Hum. Pathol. 40(10):1377-1383(2009) Noske, A., et al. Int. J. Gynecol. Pathol. 28(3):203-210(2009)
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