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SDR Antibody (Center)

Purified Rabbit Polyclonal Antibody (Pab)

  • WB - SDR Antibody (Center) AP9935c
    Anti-SDR Antibody (Center) at 1:1000 dilution + human heart lysate Lysates/proteins at 20 µg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 47 kDa Blocking/Dilution buffer: 5% NFDM/TBST.
  • IHC-P - SDR Antibody (Center) AP9935c
    SDR Antibody (Center) (Cat. #AP9935c) IHC analysis in formalin fixed and paraffin embedded lung carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the SDR Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.
  • FC - SDR Antibody (Center) AP9935c
    SDR Antibody (Center) (Cat. #AP9935c) flow cytometric analysis of NCI-H460 cells (bottom histogram) compared to a negative control cell (top histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession O95810
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 47173 Da
Antigen Region 109-135 aa
Additional Information
Gene ID 8436
Other Names Serum deprivation-response protein, Cavin-2, PS-p68, Phosphatidylserine-binding protein, SDPR {ECO:0000312|EMBL:AAD177951}
Target/Specificity This SDR antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 109-135 amino acids from the Central region of human SDR.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsSDR Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name SDPR {ECO:0000312|EMBL:AAD17795.1}
Function May play a role in targeting PRKCA to caveolae.
Cellular Location Cytoplasm, cytosol. Membrane, caveola. Note=Colocalizes with CAV1 to caveolae
Tissue Location Highly expressed in heart and lung, and expressed at lower levels in brain, kidney, liver, pancreas, placenta, and skeletal muscle.
Research Areas
Citations ( 0 )


This gene encodes a calcium-independent phospholipid-binding protein whose expression increases in serum-starved cells. This protein is a substrate for protein kinase C (PKC) phosphorylation and recruits polymerase I and transcript release factor (PTRF) to caveolae. Removal of this protein causes caveolae loss and its over-expression results in caveolae deformation and membrane tubulation.


Baig, A., et al. Proteomics 9(17):4254-4258(2009)
Hansen, C.G., et al. Nat. Cell Biol. 11(7):807-814(2009)
Ogata, T., et al. Mol. Cell. Biol. 28(10):3424-3436(2008)

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$ 295.00
$ 99.00
Cat# AP9935c
(40 western blots)
Availability: In Stock
Bulk Size
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