|Application ||WB, FC, E|
|Calculated MW||41964 Da|
|Antigen Region||369-398 aa|
|Other Names||Transcription factor Sp5, SP5|
|Target/Specificity||This SP5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 369-398 amino acids from the C-terminal region of human SP5.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||SP5 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Binds to GC boxes promoters elements. Probable transcriptional activator that has a role in the coordination of changes in transcription required to generate pattern in the developing embryo (By similarity).|
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Provided below are standard protocols that you may find useful for product applications.
SP5 binds to GC boxes promoters elements. SP5 probable transcriptional activator that has a role in the coordination of changes in transcription required to generate pattern in the developing embryo.
Chen, Y., et al. Biochem. Biophys. Res. Commun. 340(3):758-766(2006)
Suske, G., et al. Genomics 85(5):551-556(2005)
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