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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   SPR Antibody (C-term)   

SPR Antibody (C-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - SPR Antibody (C-term) AP9950B
    Anti-SPR Antibody (C-term) at 1:1000 dilution + A549 whole cell lysate Lysates/proteins at 20 µg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 28 kDa Blocking/Dilution buffer: 5% NFDM/TBST.
  • WB - SPR Antibody (C-term) AP9950B
    Western blot analysis of SPR Antibody (C-term) (Cat.#AP9950b) in mouse liver tissue lysates (35ug/lane). SPR (arrow) was detected using the purified Pab.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P35270
Reactivity Human, Mouse
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 28048 Da
Antigen Region 231-260 aa
Additional Information
Gene ID 6697
Other Names Sepiapterin reductase, SPR, SPR
Target/Specificity This SPR antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 231-260 amino acids from the C-terminal region of human SPR.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsSPR Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name SPR
Function Catalyzes the final one or two reductions in tetra- hydrobiopterin biosynthesis to form 5,6,7,8-tetrahydrobiopterin.
Cellular Location Cytoplasm.
Research Areas
Citations ( 0 )


SPR encodes an aldo-keto reductase that catalyzes the NADPH-dependent reduction of pteridine derivatives and is important in the biosynthesis of tetrahydrobiopterin (BH4). Mutations in this gene result in DOPA-responsive dystonia due to sepiaterin reductase deficiency. A pseudogene has been identified on chromosome 1.


Leu-Semenescu, S., et al. Sleep 33(3):307-314(2010) Schnetz-Boutaud, N.C., et al. Genes Brain Behav. 8(8):753-757(2009) Clot, F., et al. Brain 132 (PT 7), 1753-1763 (2009)

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$ 295.00
$ 99.00
Cat# AP9950B
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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