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YPEL5 Antibody (C-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
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- BACKGROUND
Application 
| IHC-P, WB, E |
|---|---|
| Primary Accession | P62699 |
| Other Accession | P62700, Q4R4Q6, Q3ZBE7 |
| Reactivity | Human, Mouse |
| Predicted | Bovine, Monkey |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 13842 Da |
| Antigen Region | 92-121 aa |
| Gene ID | 51646 |
|---|---|
| Other Names | Protein yippee-like 5, YPEL5 |
| Target/Specificity | This YPEL5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 92-121 amino acids from the C-terminal region of human YPEL5. |
| Dilution | WB~~1:1000 IHC-P~~1:50~100 |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | YPEL5 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | YPEL5 |
|---|---|
| Function | Component of the CTLH E3 ubiquitin-protein ligase complex that selectively accepts ubiquitin from UBE2H and mediates ubiquitination and subsequent proteasomal degradation of the transcription factor HBP1 (PubMed:29911972). Required for normal cell proliferation (By similarity). |
| Cellular Location | Nucleus {ECO:0000250|UniProtKB:Q65Z55}. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000250|UniProtKB:Q65Z55}. Cytoplasm, cytoskeleton, spindle pole {ECO:0000250|UniProtKB:Q65Z55}. Midbody {ECO:0000250|UniProtKB:Q65Z55} Note=Deteted in nucleus and at the centrosome during interphase. During mitosis, detected on the mitotic spindle, at spindle poles and at the midbody. {ECO:0000250|UniProtKB:Q65Z55} |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
info@abcepta.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
References
Hillier, L.W., et al. Nature 434(7034):724-731(2005)
Hosono, K., et al. Gene 340(1):31-43(2004)
Roxstrom-Lindquist, K., et al. Insect Mol. Biol. 10(1):77-86(2001)
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