|Application ||WB, IHC-P, FC, E|
|Other Accession||Q6AYJ2, Q5SQY2|
|Calculated MW||19196 Da|
|Antigen Region||127-155 aa|
|Other Names||Biorientation of chromosomes in cell division protein 1, Biorientation defective protein 1, Protein FAM44B, BOD1, FAM44B|
|Target/Specificity||This FAM44B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 127-155 amino acids from the C-terminal region of human FAM44B.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||FAM44B Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Required for proper chromosome biorientation through the detection or correction of syntelic attachments in mitotic spindles.|
|Cellular Location||Cytoplasm, cytoskeleton, microtubule organizing center, centrosome Chromosome, centromere, kinetochore Note=Localizes at the centrosomes throughout the cell cycle, only dissociating during cytokinesis. Localizes at the kinetochore from prometaphase until anaphase|
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Provided below are standard protocols that you may find useful for product applications.
FAM44B required for proper chromosome biorientation through the detection or correction of syntelic attachments in mitotic spindles.
Ling, H., et al. Obesity (Silver Spring) 17(4):737-744(2009)
Porter, I.M., et al. J. Cell Biol. 179(2):187-197(2007)
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