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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   PHTNS Antibody (N-term)   

PHTNS Antibody (N-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - PHTNS Antibody (N-term) AP9994a
    Western blot analysis of PHTNS Antibody (N-term) (Cat. #AP9994a) in Ramos cell line lysates (35ug/lane). PHTNS (arrow) was detected using the purified Pab.
  • IHC-P - PHTNS Antibody (N-term) AP9994a
    PHTNS Antibody (N-term) (Cat. #AP9994a) IHC analysis in formalin fixed and paraffin embedded human spleen tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the PHTNS Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.
  • FC - PHTNS Antibody (N-term) AP9994a
    PHTNS Antibody (N-term) (Cat. #AP9994a) flow cytometric analysis of Ramos cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q6NYC8
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 67943 Da
Antigen Region 192-220 aa
Additional Information
Gene ID 170954
Other Names Phostensin, Protein phosphatase 1 F-actin cytoskeleton-targeting subunit, Protein phosphatase 1 regulatory subunit 18, PPP1R18, HKMT1098, KIAA1949
Target/Specificity This PHTNS antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 192-220 amino acids from the N-terminal region of human PHTNS.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsPHTNS Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name PPP1R18
Synonyms HKMT1098, KIAA1949
Function Isoform 1: May target protein phosphatase 1 to F-actin cytoskeleton.
Cellular Location Isoform 1: Cytoplasm, cytoskeleton
Tissue Location Isoform 4 is predominantly expressed in leukocytes and spleen.
Research Areas
Citations (0)

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PHTNS interacts with regulatory subunits that target the enzyme to different cellular locations and change its activity toward specific substrates. Phostensin is a regulatory subunit that targets PP1 to F-actin cytoskeleton。


Lai, N.S., et al. Biochem. Biophys. Res. Commun. 387(4):676-681(2009)
Barcellos, L.F., et al. PLoS Genet. 5 (10), E1000696 (2009)
Kao, S.C., et al. Biochem. Biophys. Res. Commun. 356(3):594-598(2007)

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$ 295.00
$ 99.00
Cat# AP9994a
(40 western blots)
Availability: In Stock
Bulk Size
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