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>   home   >   Products   >   Primary Antibodies   >   Antibody Collections   >   Infectious Disease and Small Molecules   >   Monoclonal Antibody to Tacrolimus (FK-506) [B246M]   

Monoclonal Antibody to Tacrolimus (FK-506) [B246M]

     
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
EIA
Host Mouse
Clonality Monoclonal
Isotype IgM
Clone Names B246M
Immunogen FK-506 BSA Conjugate
Purification Euglobulin Precipitation and Dialysis
Additional Information
Target/Specificity Detects FK-506, a macrolide with similar but more potent immunosuppressant activity than cyclosporine. It is a 23-membered lactone produced by the bacteria Streptomyces tsukubaensis. FK-506 inhibits signal transduction and interleukin-2 transcription in CD4+ T helper lymphocytes, and is mainly used after allogenic organ transplantation to reduce organ rejection.
Preservative 0.09% Sodium Azide
Format Purified, Liquid
Storage Short term store at 2-8°C. Long term aliquot and store at -20°C. Prepare working dilution only prior to immediate use. Avoid multiple freeze/thaw cycles.
PrecautionsMonoclonal Antibody to Tacrolimus (FK-506) [B246M] is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
Citations (0)

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References

The reference listed below is for research purposes only:Letko, E., et al., (1999), “Tacrolimus (FK506)”, Ann. Allergy Asthma Immunol., 83: 179-189.

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$ 613.33
Cat# AR11359
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