|Application ||WB, IHC, E, DB|
|Other Names||IL-1α; IL1A; IL1-ALPHA|
|Reconstitution & Storage||Store at -20°C. Avoid freeze / thaw cycles. Short term storage +2°C-+8°C|
|Precautions||INTERLEUKIN 1 ALPHA (IL-1a) Antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
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Provided below are standard protocols that you may find useful for product applications.
Interleukin 1α is a proinflammatory cytokine produced by a wide variety of cell types, including macrophages, osteoblasts, monocytes and hepatocytes. Circulating levels of are normally low and only rise after stimulation by agents such as those produced by inflammation, infection or microbial endotoxins. IL-1α possesses a wide variety of biological activities and exerts its effects by binding to specific cell surface receptors. . RANDOX recombinant IL-1 α -chain comprises a 159 amino acid fragment (113-271) corresponding to the mature IL-1 α chain and is expressed in E. coli with an amino-terminal hexahistidine tag. This product is for research use only and is not intended for diagnostic or therapeutic use.
Dinarello, C.A. (2002) Clin. Exp. Rheumatol. 20(5 s.27): S1-13.
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