|Application ||WB, IHC, E, DB|
|Other Names||IL-4; Interleukin-4; IL4; B-cell stimulatory factor 1; BSF-1; Lymphocyte stimulatory factor 1; Binetrakin; Pitrakinra|
|Reconstitution & Storage||Store at -20°C. Avoid freeze / thaw cycles. Short term storage +2°C-+8°C|
|Precautions||INTERLEUKIN 4 (IL-4) Affinity Purified Antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
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Provided below are standard protocols that you may find useful for product applications.
Interleukin-4 is a pleiotropic cytokine produced primarily by activated T lymphocytes, basophils and mast cells. Multiple immune response-modulating functions are performed by IL-4 on a variety of cell types and it has an important role in the regulator of isotype switching, induction of IgE production in B lymphocytes and differentiation of precursor T helper cells. IL-4 binds to both membrane-bound and secreted soluble IL-4 receptors. RANDOX recombinant IL-4 comprises a 129 amino acid fragment (25-153) corresponding to the mature IL-4 protein and is expressed in E. coli with an amino-terminal hexahistidine tag. This product is for research use only and is not intended for diagnostic or therapeutic use.
Ohara, J. (1989) Year Immunol. 5 : 126-159. Beckmann, M.P. et al. (1992) Chem. Immunol. 51 : 107- 135
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