|Application ||WB, IHC, E, DB|
|Other Names||L-Selectin; Leukocyte Selectin; L-SEL; Leukocyte adhesion molecule; LAM-1; Leukocyte cell adhesion molecule LECAM-1; TQ1; CD62L; Leukocyte surface antigen Leu-8; DREG; lymph node homing receptor LNHR; MEL-15|
|Reconstitution & Storage||Store at -20°C. Avoid freeze / thaw cycles. Short term storage +2°C-+8°C|
|Precautions||L-SELECTIN Affinity Purified Antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
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L-Selectin belongs to a family of divalent cationdependent carbohydrate-binding glycoproteins or adhesion molecules. L-Selectin is expressed constitutively on lymphocytes, monocytes and granulocytes and interacts specifically with carbohydrate groups on activated endothelial cells. L-Selectin may be shed by proteolytic cleavage and circulating levels in biological fluids may be used as an indicator of various pathological conditions. RANDOX recombinant human L-selectin comprises a 294 amino acid fragment (39-332) corresponding to the mature L-Selectin extracellular domain and is expressed in E. coli with an amino-terminal hexahistidine tag. This product is for research use only and is not intended for diagnostic or therapeutic use.
Tedder, T.F et al. (1990) J. Immunol. 144 (2): 532-540. Schleiffenbaum, B. et al. (1992) J. Cell Biol. 119 (1): 229- 238.
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