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>   home   >   Products   >   Primary Antibodies   >   NALTREXONE Antibody   


Purified Sheep Polyclonal Antibody

Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Host Sheep
Clonality Polyclonal
Additional Information
Other Names Naltrexone hydrochloride; Revia; Depade; Vivitrol
Reconstitution & Storage Store at -20°C. Avoid freeze / thaw cycles. Short term storage +2°C-+8°C
PrecautionsNALTREXONE Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Citations (0)

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Naltrexone is an opioid receptor antagonist used primarily in the management of alcohol dependence and opioid dependence. It is marketed in generic form as its hydrochloride salt, naltrexone hydrochloride, and marketed under the trade names Revia and Depade. Naltrexone and its active metabolite 6-β-naltrexol are competitive antagonists at æ- and β-opioid receptors, and to a lesser extent at β-opioid receptors.[1] The plasma half-life of naltrexone is about 4 h, for 6-β-naltrexol 13 h. The blockade of opioid receptors is the basis behind its action in the management of opioid dependence - it reversibly blocks or attenuates the effects of opioids. Its use in alcohol (ethanol) dependence has been studied and has been shown to be effective. Naltrexone is metabolized mainly to 6β-naltrexol by the liver enzyme dihydrodiol dehydrogenase. Other metabolites include 2-hydroxy-3-methoxy-6β-naltrexol and 2-hydroxy-3-methoxy-naltrexone. These are then further metabolized by conjugation with glucuronide.


1. Shader, RI. Antagonists, Inverse Agonists, and Protagonists. Journal of Clinical Psychopharmacology. 2003 Aug; 23(4):321?322. PMID 12920406

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$ 390.00
Cat# ARD10252
(40 western blots)
Availability: 2-3 days
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