|Application ||WB, IHC, E, DB|
|Other Names||Pyruvate kinase; Pyruvate kinase M1/M2; Pyruvate kinase M2; Pyruvate kinase muscle isozyme; Pyruvate kinase 2/3; Cytosolic thyroid hormone-binding protein; CTHBP; THBP1; p58; M2-PK; Tumor M2-PK; PKM2|
|Reconstitution & Storage||Store at -20°C. Avoid freeze / thaw cycles. Short term storage +2°C-+8°C|
|Precautions||TUMOUR TYPE M2 PYRUVATE KINASE (M2PK) Antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
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Provided below are standard protocols that you may find useful for product applications.
Pyruvate kinase is a key enzyme in the glycolytic pathway. The M2 isoenzyme of pyruvate kinase is specifically expressed at high levels in tumour cells, and can be measured in plasma of patients with advanced breast cancer. The marker is useful for measuring disease activity, sensitivity to chemotherapy and recurrence. RANDOX recombinant human M2PK is expressed in E. coli with an amino-terminal hexahistidine tag. This product is for research use only and is not intended for diagnostic or therapeutic use
Luftner D. et al. (2000) Anticancer Res. 20(6D): 5077-82
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