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Bonzo Antibody

  • WB - Bonzo Antibody ASC10082
    Western blot analysis of Bonzo in human spleen tissue lysate with Bonzo antibody at 1 µg/mL in (A) the absence or (B) the presence of blocking peptide.
  • IHC - Bonzo Antibody ASC10082
    Immunohistochemistry of Bonzo in human spleen tissue with Bonzo antibody at 20 µg/mL.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession O00574
Other Accession AAB64221, 2253422
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype IgG
Calculated MW Predicted: 38 kDa

Observed: 43 kDa
Application Notes Bonzo antibody can be used for detection of Bonzo by Western blot at 0.5 µg/mL. Antibody can also be used for immunohistochemistry starting at 20 µg/mL. For immunofluorescence start at 20 µg/mL.
Additional Information
Gene ID 10663
Other Names Bonzo Antibody: BONZO, CD186, STRL33, TYMSTR, BONZO, C-X-C chemokine receptor type 6, CDw186, CXC-R6, chemokine (C-X-C motif) receptor 6
Target/Specificity CXCR6;
Reconstitution & Storage Bonzo antibody can be stored at 4℃ for three months and -20℃, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
PrecautionsBonzo Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name CXCR6
Function Receptor for the C-X-C chemokine CXCL16. Used as a coreceptor by SIVs and by strains of HIV-2 and m-tropic HIV-1.
Cellular Location Cell membrane; Multi-pass membrane protein.
Tissue Location Expressed in lymphoid tissues and activated T cells
Research Areas
Citations (0)

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Bonzo Antibody: Human immunodeficiency virus (HIV) and simian immunodeficiency virus (SIV) require coreceptors, in addition to CD4, to infect target cells. Some G protein-coupled receptors including CCR5, CXCR4, CCR3, and CCR2b in the chemokine receptor family have been identified as HIV coreceptors. An orphan G protein-coupled receptor was recently cloned and designated Bonzo, STRL33 and TYMSTR, and identified as HIV and SIV coreceptor. Bonzo/STRL33 serves as coreceptor for SIV, HIV-2 and HIV-1. The messenger RNA of Bonzo/STRL33 is expressed in lymphoid tissues and activated peripheral blood lymphocytes.


Deng HK, Unutmaz D, KewalRamani VN, et al. Expression cloning of new receptors used by simian and human immunodeficiency viruses. Nature 1997; 388:296-300.
Liao F, Alkhatib G, Peden KW, et al. STRL33, A novel chemokine receptor-like protein, functions as a fusion cofactor for both macrophage-tropic and T cell line-tropic HIV-1. J. Exp. Med. 1997; 185:2015-23.
Alkhatib G, Liao F, Berger EA, et al. A new SIV co-receptor, STRL33. Nature 1997; 388:238.
Loetscher M, Amara A, Oberlin E, et al. TYMSTR, a putative chemokine receptor selectively expressed in activated T cells, exhibits HIV-1 coreceptor function. Curr. Biol. 1997; 7:652-60.

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$ 310.00
Cat# ASC10082
(40 western blots)
Availability: 5-7days
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