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>   home   >   Products   >   Primary Antibodies   >   Immunology   >   IL-21 Receptor Antibody   

IL-21 Receptor Antibody

  • WB - IL-21 Receptor Antibody ASC10143
    Western blot analysis of IL-21 receptor expression in human Raji cell lysate with IL-21 Receptor antibody at 1 µg /ml.
  • IHC - IL-21 Receptor Antibody ASC10143
    Immunohistochemistry of IL-21 receptor in rat lung with IL-21 receptor antibody at 10 µg/mL.
  • IF - IL-21 Receptor Antibody ASC10143
    Immunofluorescence of IL-21 Receptor in Rat Lung cells with IL-21 Receptor antibody at 20 µg/mL.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q9HBE5
Other Accession NP_068570, 11141869
Reactivity Human, Mouse, Rat
Host Rabbit
Clonality Polyclonal
Isotype IgG
Calculated MW 60 kDa
Application Notes IL-21 receptor antibody can be used for detection of IL-21 receptor by Western blot at 1 µg/mL. An approximately 60 kDa band can be detected. Antibody can also be used for immunohistochemistry starting at 10 µg/mL. For immunofluorescence start at 20 µg/mL.
Additional Information
Gene ID 50615
Other Names IL-21 Receptor Antibody: NILR, CD360, NILR, UNQ3121/PRO10273, Interleukin-21 receptor, Novel interleukin receptor, IL-21 receptor, interleukin 21 receptor
Target/Specificity IL21R;
Reconstitution & Storage IL-21 Receptor antibody can be stored at 4℃ for three months and -20℃, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
PrecautionsIL-21 Receptor Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name IL21R
Synonyms NILR
Function This is a receptor for interleukin-21.
Cellular Location Membrane; Single-pass type I membrane protein
Tissue Location Selectively expressed in lymphoid tissues. Most highly expressed in thymus and spleen
Research Areas
Citations (0)

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IL-21 Receptor Antibody: A novel cytokine related to IL-2 and IL-15 was recently identified and designated IL-21. The receptor for IL-21 (IL-21R, also termed NILR for novel Interleukin receptor) is a new member of the class I cytokine receptor family. IL-21R forms a complex with the common cytokine receptor gamma chain, gammac, and mediates IL-21 signaling. Both IL-21R and the gammac are necessary for the IL-21 function. IL-21 and its receptor activate JAK-STAT signaling pathway. IL-21R is expressed in spleen, thymus, natural killer (NK), T and B cell lines. IL-21 plays a role in the proliferation and maturation of NK, B and T cell populations.


Parrish-Novak J, Dillon SR, Nelson A, et al. Interleukin 21 and its receptor are involved in NK cell expansion and regulation of lymphocyte function. Nature. 2000;408(6808):57-63.
Ozaki K, Kikly K, Michalovich D, et al.  Cloning of a type I cytokine receptor most related to the IL-2 receptor β chain. Proc Natl Acad Sci USA. 2000;97(21):11439-44.
Asao H, Okuyama C, Kumaki S, et al. the common γ-chain is an indispensable subunit of the IL-21 receptor complex. J Immunol. 2001;167(1):1-5.
Vosshenrich CA, Di Santo JP. Cytokines: IL-21 joins the γ(c)-dependent network.Curr Biol. 2001;11(5):R175-7.

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$ 310.00
Cat# ASC10143
(40 western blots)
Availability: 5-7days
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