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>   home   >   Products   >   Primary Antibodies   >   Cell Biology   >   Bcl-G Antibody   

Bcl-G Antibody

  • WB - Bcl-G Antibody ASC10203
    Western blot analysis of Bcl-G in U937 cell lysates with Bcl-G antibody at (A) 2.5 and (B) 5 µg/mL.
  • IHC - Bcl-G Antibody ASC10203
    Immunohistochemical staining of mouse testis tissue using Bcl-G antibody at 2 µg/mL.
  • IF - Bcl-G Antibody ASC10203
    Immunofluorescence of Bcl-G in Mouse Testis cells with Bcl-G antibody at 10 µg/mL.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q9BZR8
Other Accession NM_030766, 13540528
Reactivity Human, Mouse, Rat
Host Rabbit
Clonality Polyclonal
Isotype IgG
Calculated MW 36598 Da
Application Notes Bcl-G antibody can be used for detection of Bcl-G by Western blot at 2.5 to 5 µg/mL. Antibody can also be used for immunohistochemistry starting at 2 µg/mL. For immunofluorescence start at 10 µg/mL.
Additional Information
Gene ID 79370
Other Names Bcl-G Antibody: BCLG, BCLG, Apoptosis facilitator Bcl-2-like protein 14, Apoptosis regulator Bcl-G, Bcl2-L-14, BCL2-like 14 (apoptosis facilitator)
Target/Specificity BCL2L14; Although antibody should react with both isoforms, only the Bcl-GS protein has been observed
Reconstitution & Storage Bcl-G antibody can be stored at 4℃ for three months and -20℃, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
PrecautionsBcl-G Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name BCL2L14
Synonyms BCLG
Function Plays a role in apoptosis.
Cellular Location Cytoplasm. Isoform 2: Endomembrane system. Note=Predominantly localized to cytosolic organelles
Tissue Location Isoform 1 is widely expressed. Isoform 2 is testis-specific.
Research Areas
Citations (0)

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Bcl-G Antibody: Members in the Bcl-2 family are critical regulators of apoptosis by either inhibiting or promoting cell death. Bcl-2 homology 3 (BH3) domain is a potent death domain. BH3 domain containing pro-apoptotic proteins, including Bad, Bax, Bid, Bik, and Hrk, form a growing subclass of the Bcl-2 family. A novel BH3 domain containing protein was recently identified and designated Bcl-G. The mRNA of Bcl-G encodes 2 isoforms, Bcl-GL, which is widely expressed in multiple tissues, and Bcl-GS, which is only found in testis. The Bcl-GS protein is predominantly localized to cytoplasmic organelles whereas Bcl-GL was distributed throughout the cytosol. Overexpression of either protein induced apoptosis, although Bcl-GS was far more potent than Bcl-GS. Apoptosis induction was dependent on the BH3 domain and could be suppressed by co-expression with the anti-apoptotic Bcl-XL protein.


Cory S, Huang DCS, and Adams JM. The Bcl-2 family: roles in cell survival and oncogenesis. Oncogene 2003; 22:8590-607.
Heiser D, Labi V, Erlacher M, et al. The Bcl-2 protein family and its role in the development of neoplastic disease. Exp. Geron.. 2004; 39:1125-35.
Guo B, Godzik A, and Reed JC. Bcl-G, a novel pro-apoptotic member of the Bcl-2 family. J. Biol. Chem. 2000; 276:2780-5.

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$ 310.00
Cat# ASC10203
(40 western blots)
Availability: 5-7days
Bulk Size
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