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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   T-cadherin Antibody   

T-cadherin Antibody

     
  • WB - T-cadherin Antibody ASC10345
    Western blot analysis of Aldh5A1 in human liver tissue lysate with Aldh5A1 antibody at (A) 0.25 and (B) 0.5 µg/mL.
  • WB - T-cadherin Antibody ASC10345
    Western blot analysis of SUMO2/3 in Jurkat cell lysate with SUMO2/3 antibody at (A) 1 and (B) 2 µg/mL.
  • SPECIFICATION
  • CITATIONS
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P, IF, E
Primary Accession O75355
Other Accession NP_001248, 956
Reactivity Human, Mouse
Host Rabbit
Clonality Polyclonal
Isotype IgG
Calculated MW Predicted: 78, 84 kDa

Observed: 85 kDa
Application Notes T-cadherin antibody can be used for the detection of T-cadherin by Western blot at 0.5 - 1 μg/mL. Antibody can also be used for for immunohistochemistry starting at 5 μg/mL and immunocytochemistry starting at 20 μg/mL. For immunofluorescence start at 20 μg/mL.
Additional Information
Gene ID 956
Other Names T-cadherin Antibody: HB6, CD39L3, NTPDase-3, Ectonucleoside triphosphate diphosphohydrolase 3, CD39 antigen-like 3, NTPDase 3, ectonucleoside triphosphate diphosphohydrolase 3
Target/Specificity T-cadherin antibody was raised against a 15 amino acid synthetic peptide from near the amino terminus of human T-cadherin.

The immunogen is located within amino acids 150 - 200 of T-cadherin.
Reconstitution & Storage T-cadherin antibody can be stored at 4℃ for three months and -20℃, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
PrecautionsT-cadherin Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name ENTPD3
Synonyms CD39L3
Function Has a threefold preference for the hydrolysis of ATP over ADP.
Cellular Location Membrane; Multi-pass membrane protein
Tissue Location Expressed in adult brain, pancreas, spleen and prostate. Moderate or low expression is seen in most tissues. Not expressed in liver and peripheral blood leukocytes
Research Areas
Citations (0)

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Background

T-cadherin Antibody: T-cadherin was initially identified as cadherin-type cell adhesion molecule expressed in various neuronal populations in a temporally and spatially restricted pattern during axon growth. T-cadherin is an atypical member of the cadherin family because it does not possess the typical transmembrane and cytoplasmic domains but is instead anchored to the plasma membrane by glycosylphosphatidylinositol (GPI) linkage. T-cadherin may play a role in malignant tumor development as loss of the chromosome locus containing the T-cadherin gene correlates with the development of a variety of cancers. Recently it has been shown that T-cadherin can act as a receptor for hexameric and high-molecular weight forms of adiponectin, suggesting that T-cadherin may also play a role in metabolic regulation.

References

Ranscht B and Dours-Zimmerman MT. T-cadherin, a novel cadherin cell adhesion molecule in the nervous system lacks the conserved cytoplasmic region. Neuron 1991; 7:391-402.
Ivanov DB, Philippova MP, and Tkachuk VA. Structure and functions of classical cadherins Biochemistry (Moscow) 2001; 66:1175-66.
Takeuchi T, Misaki A, Chen BK, et al. H-cadherin expression in breast cancer. Histopathology 1999; 35:87-88.
Sato M, Mori Y, Sakurada A, et al. The H-cadherin (CDH13) gene is inactivated in human lung cancer. Hum. Gen. 1998; 103:96-101.

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$ 320.00
Cat# ASC10345
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