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Neuritin Antibody

  • WB - Neuritin Antibody ASC10524
    Western blot analysis of neuritin in Daudi cell lysate with neuritin antibody at (A) 5 and (B) 10 µg/mL.
  • IHC - Neuritin Antibody ASC10524
    Immunohistochemistry of Neuritin in mouse heart tissue with Neuritin antibody at 5 µg/mL.
  • IF - Neuritin Antibody ASC10524
    Immunofluorescence of Neuritin in Mouse Heart cells with Neuritin antibody at 20 µg/mL.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q9NPD7
Other Accession NP_057672, 7706123
Reactivity Human, Mouse
Host Rabbit
Clonality Polyclonal
Isotype IgG
Calculated MW Predicted: 16 kDa

Observed: 15 kDa
Application Notes Neuritin antibody can be used for detection of Neuritin by Western blot at 5 and 10 µg/mL. Antibody can also be used for immunohistochemistry starting at 5 µg/mL. For immunofluorescence start at 20 µg/mL.
Additional Information
Gene ID 51299
Other Names Neuritin Antibody: NRN, dJ380B8.2, NRN, Neuritin, neuritin 1
Target/Specificity NRN1;
Reconstitution & Storage Neuritin antibody can be stored at 4℃ for three months and -20℃, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
PrecautionsNeuritin Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name NRN1
Synonyms NRN
Function Promotes neurite outgrowth and especially branching of neuritic processes in primary hippocampal and cortical cells.
Cellular Location Cell membrane; Lipid-anchor, GPI-anchor. Cell junction, synapse
Research Areas
Citations (0)

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Neuritin Antibody: As the nervous system of a complex organism develops, it establishes functional networks through the growth and retraction of synaptic connections from growing axons and dendrites. This synaptic remodeling involves neuro-transmitter signaling, activation of neurotrophin receptors and alterations in gene expression. One such gene whose expression is increased by neural activity is neuritin, a GPI-anchored protein that is expressed in postmitotic differentiating neurons of the developing nervous system. Its expression is also induced by the neurotrophins BDNF and NT-3. Purified recombinant neuritin promotes neurite outgrowth and arborization in primary embryonic neuronal cultures, suggesting that neuritin may play a role as a downstream effector of activity-induced neurite outgrowth. More recent experiments have shown that neuritin is required for the androgen-induced axonal elongation in motor neurons and is upregulated following spinal cord injury, suggesting that neuritin may also play a role in survival and axonal regeneration.


Li Z and Sheng M. Some assembly required: the development of neuronal synapses. Nat. Rev. Mol. Cell Biol. 2003; 4:833-41.
Naeve GS, Ramakrishnan M, Kramer R, et al. Neuritin: A gene induced by neural activity and neurotrophins that promotes neuritogenesis. Proc. Natl. Acad. Sci. USA 1997; 94:2648-53.
Marron TU, Guerini V, Rusmini P, et al. Androgen-induced neurite outgrowth is mediated by neuritin in motor neurons. J. Neurochem. 2005; 92:10-20.
Di Giovanni S, De Biase A, Yakovlev A, et al. In vivo and in vitro characterization of novel neuronal plasticity factors identified following spinal cord injury. J. Biol. Chem. 2005; 280:2084-91.

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$ 330.00
Cat# ASC10524
Availability: 5-7days
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