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STEAP2 Antibody

  • WB - STEAP2 Antibody ASC10573
    Western blot analysis of STEAP2 in human prostate tissue lysate with STEAP2 antibody at 1 µg/mL.
  • IHC - STEAP2 Antibody ASC10573
    Immunohistochemistry of STEAP2 in human colon tissue with STEAP2 antibody at 2.5 µg/mL.
  • IF - STEAP2 Antibody ASC10573
    Immunofluorescence of STEAP2 in Human Colon cells with STEAP2 antibody at 20 µg/mL.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q8NFT2
Other Accession Q8NFT2, 83286886
Reactivity Human, Mouse
Host Rabbit
Clonality Polyclonal
Isotype IgG
Calculated MW Predicted: 54 kDa

Observed: 55 kDa
Application Notes STEAP2 antibody can be used for detection of STEAP2 by Western blot at 1 - 2 µg/mL. Antibody can also be used for immunohistochemistry starting at 2.5 µg/mL. For immunofluorescence start at 20 µg/mL.
Additional Information
Gene ID 261729
Target/Specificity STEAP2; This STEAP2 antibody does not cross-react with other STEAP proteins.
Reconstitution & Storage STEAP2 antibody can be stored at 4℃ for three months and -20℃, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
PrecautionsSTEAP2 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Synonyms PCANAP1, STAMP1
Function Metalloreductase that has the ability to reduce both Fe(3+) to Fe(2+) and Cu(2+) to Cu(1+). Uses NAD(+) as acceptor (By similarity).
Cellular Location Endosome membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein
Tissue Location Expressed at high levels in prostate and at significantly lower levels in heart, brain, kidney, pancreas, and ovary.
Research Areas
Citations (0)

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STEAP2 Antibody: The six-transmembrane epithelial antigen of prostate 2 (STEAP2) is a member of a family of metalloreductases identified as cell-surface antigens in prostate tissue. Similar to two other members of the STEAP family (STEAP 3 and STEAP4), STEAP2 promotes both iron and copper reduction. STEAP2 expression in transfected cells also correlated with iron or copper uptake, suggesting that the STEAP family of proteins may function to stimulate iron and copper uptake. STEAP2 is widely expressed in many tissues in the plasma membrane, but is most highly expressed in prostate. At least three isoforms of STEAP2 are known to exist.


Porkka KP, Helenius MA and Visakorpi T. Cloning and characterization of a novel six-transmembrane protein STEAP2, expressed in normal and malignant prostate. Lab Invest.2002; 82:1573-82.
Ohgami RS, Campagna DR, McDonald A, et al. The Steap proteins are metalloreductases. Blood2006; 108:1388-94.
Ohgami RS, Campagna DR, Greer EL, et al. Identification of a ferrireductase required for efficient transferrin-dependent iron uptake in erythroid cells. Nat. Genet.2005; 37:1264-9.

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$ 310.00
Cat# ASC10573
(40 western blots)
Availability: 5-7days
Bulk Size
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