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Cathelicidin Antibody

  • WB - Cathelicidin Antibody ASC10628
    Western blot analysis of Cathelicidin in Human spleen tissue lysate with Cathelicidin antibody at 1 µg/mL.
  • IHC - Cathelicidin Antibody ASC10628
    Immunohistochemistry of Catheli-cidin in human spleen tissue with Cathelicidin antibody at 5 µg/mL.
  • IF - Cathelicidin Antibody ASC10628
    Immunofluorescence of Cathelicidin in Human Spleen cells with Cathelicidin antibody at 20 µg/mL.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P49913
Other Accession NP_004336, 39753970
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype IgG
Calculated MW Predicted: 19 kDa

Observed: 18 kDa
Application Notes Cathelicidin antibody can be used for detection of Cathelicidin by Western blot at 1 µg/mL. Antibody can also be used for immunohistochemistry starting at 5 µg/mL. For immunofluorescence start at 20 µg/mL.
Additional Information
Gene ID 820
Target/Specificity CAMP;
Reconstitution & Storage Cathelicidin antibody can be stored at 4℃ for three months and -20℃, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
PrecautionsCathelicidin Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Synonyms CAP18, FALL39
Function Binds to bacterial lipopolysaccharides (LPS), has antibacterial activity.
Cellular Location Secreted.
Tissue Location Expressed in bone marrow and testis and neutrophils
Research Areas
Citations (0)

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Cathelicidin Antibody: One component of host defense at mucosal surfaces is epithelial-derived antimicrobial peptides. Cathelicidins are one family of antimicrobial peptides characterized by conserved pro-peptide sequences that have been identified in epithelial tissues and some myeloid cells of humans and animals. LL-37/hCAP-18 is the only Cathelicidin found in humans and is expressed in inflammatory and epithelial cells. The presence of these molecules is essential for defense against invasive bacterial infection in skin. Besides their direct antimicrobial function, Cathelicidins have multiple roles in mediating innate and adaptive immunity, such as endotoxin neutralizing, angiogenesis, wound healing and promoting neutrophil chemotaxis and mast cell recruitment. Finally, Cathelicidin antimicrobial peptides qualify as prototypes of innovative drugs that may be used to treat infection and/or modulate the immune response.


Zaiou M and Gallo RL. Cathelicidins, essential gene-encoded mammalian antibiotics. J. Mol. Med. 2002; 80:549-61.
Agerberth B, Gunne H, Odeberg J, et al. FALL-39, a Putative Human Peptide Antibiotic, is Cysteine-Free and Expressed in Bone Marrow and Testis. Proc. Natl. Acad. Sci. USA 1995; 92:195-9.
Nizet V, Ohtake T, Lauthe X, et al. Innate antimicrobial peptide protects the skin from invasive bacterial infection. Nature 2001; 414:454-7.
Koczulla R, von Degenfeld G, Kupatt C, et al. An angiogenic role for the human peptide antibiotic LL-37/hCAP-18. J. Clin. Invest. 2003; 111:1665-72.

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$ 310.00
Cat# ASC10628
(40 western blots)
Availability: 5-7days
Bulk Size
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