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Slitrk3 Antibody

  • WB - Slitrk3 Antibody ASC10641
    Western blot analysis of Slitrk3 in SK-N-SH cell lysate with Slitrk3 antibody at (A) 0.5 and (B) 1 µg/mL.
  • IHC - Slitrk3 Antibody ASC10641
    Immunohistochemistry of Slitrk3 in human brain tissue with Slitrk3 antibody at 2.5 µg/mL.
  • IF - Slitrk3 Antibody ASC10641
    Immunofluorescence of slitrk3 in human brain tissue with slitrk3 antibody at 20 µg/mL.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession O94933
Other Accession O94933, 215273885
Reactivity Human, Mouse
Host Rabbit
Clonality Polyclonal
Isotype IgG
Calculated MW 108934 Da
Application Notes Slitrk3 antibody can be used for detection of Slitrk3 by Western blot at 0.5 - 1 µg/mL. Antibody can also be used for immunohistochemistry starting at 2.5 µg/mL. For immunofluorescence start at 20 µg/mL.
Additional Information
Gene ID 22865
Target/Specificity SLITRK3; This antibody is predicted to have no cross-reactivity to other Slitrk proteins.
Reconstitution & Storage Slitrk3 antibody can be stored at 4℃ for three months and -20℃, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
PrecautionsSlitrk3 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Synonyms KIAA0848
Function Suppresses neurite outgrowth.
Cellular Location Membrane; Single-pass type I membrane protein
Tissue Location Expressed in the occipital lobe of the cerebral cortex of the brain. Expressed at higher levels in some astrocytic brain tumors such as astrocytomas, oligodendrogliomas, glioblastomas, gangliogliomas and primitive neuroectodermal tumors.
Research Areas
Citations (0)

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Slitrk3 Antibody: SLIT and NTRK-like family 3 (Slitrk3) is a member a protein family consisting of six homologous transmembrane proteins (Slitrk1-6) that share two conserved leucine-rich repeat domains in the extracellular domain and have significant homology to Slit, a secreted axonal growth-controlling protein. These proteins are also homologous to trk neurotrophin receptors in their intracellular domains. Expression of Slitrk proteins is highly restricted to neural and brain tumor tissues, but varies within the protein family. Like every other Slitrk protein except Slitrk1, overexpression of Slitrk3 inhibited neurite outgrowth in cultured neurons, suggesting that these proteins are involved in the control of neurite outgrowth.


Aruga J and Mikoshiba K. Identification and characterization of Slitrk, a novel transmembrane protein family controlling neurite outgrowth. Mol. Cell Neurosci.2003; 24:117-29.
Aruga J, Yokota N, and Mikoshiba K. Human SLITRK family genes: genomic organization and expression profiling in normal and brain tumor tissue. Gene2003; 315:87-94.

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$ 310.00
Cat# ASC10641
(40 western blots)
Availability: 5-7days
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