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BICD1 Antibody

  • WB - BICD1 Antibody ASC10719
    Western blot analysis of BICD1 in Daudi cell lysate with BICD1 antibody at 1 µg/mL in (A) the absence and (B) the presence of blocking peptide.
  • ICC - BICD1 Antibody ASC10719
    Immunocytochemistry of BICD1 in Daudi cells with BICD1 antibody at 2.5 µg/mL.
  • IF - BICD1 Antibody ASC10719
    Immunofluorescence of BICD1 in Daudi cells with BICD1 antibody at 20 µg/mL.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q96G01
Other Accession NP_001705, 51039802
Reactivity Human, Mouse, Rat
Host Rabbit
Clonality Polyclonal
Isotype IgG
Calculated MW 110750 Da
Application Notes BICD1 antibody can be used for detection of BICD1 by Western blot at 1 µg/mL. Antibody can also be used for immunocytochemistry starting at 2.5 µg/mL. For immunofluorescence start at 10 µg/mL.
Additional Information
Gene ID 636
Target/Specificity BICD1; At least two isoforms of BICD1 are known to exist; this antibody will only recognize the larger isoform.
Reconstitution & Storage BICD1 antibody can be stored at 4℃ for three months and -20℃, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
PrecautionsBICD1 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name BICD1
Function Regulates coat complex coatomer protein I (COPI)- independent Golgi-endoplasmic reticulum transport by recruiting the dynein-dynactin motor complex.
Cellular Location Golgi apparatus.
Tissue Location Expressed in the brain, heart and skeletal muscle
Citations (0)

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BICD1 Antibody: BICD1 was initially identified as the human homolog to Drosophila Bicaudal-D protein that forms part of the cytoskeleton and mediates the correct sorting of mRNAs for oocyte- and axis-determining factors during oogenesis. BICD1 can bind to dynein-dynactin and co-localizes with Rab6A on the trans-Golgi network and cytoplasmic vesicles, suggesting BICD1 regulates COPI-independent Golgi-ER transport. BICD1 will also interact with Rab6B, a Rab6 isoform that is expressed primarily in brain. Live cell imaging showed bi-directional movement of Rab6B structures in SK-N-SH neurites, indicating that BICD1 is involved in the Rab6B regulation of retrograde cargo transport in neuronal cells.


Baens M and Marynen P. A human homologue (BICD1) of the drosophila bicaudal-D gene. Genomics1997; 45:601-6.
Matanis T, Akhmanova A, Wulf P, et al. Bicaudal-D regulates COPI-independent Golgi-ER transport by recruiting the dynein-dynactin motor complex. Nat. Cell Biol.2002; 986-92.
Wanshers BF, van de Vorstenbosch R, Schlager MA, et al. A role for the Rab6B Bicaudal-D1 interaction in retrograde transport in neuronal cells. Exp. Cell Res.2007; 313:3408-20.

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$ 320.00
Cat# ASC10719
Availability: 5-7days
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