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>   home   >   Products   >   Primary Antibodies   >   Stem Cells   >   BMP15 Antibody   

BMP15 Antibody

     
  • IHC - BMP15 Antibody ASC10739
    Immunohistochemistry of BMP15 in human prostate tissue with BMP15 antibody at 10 µg/mL
  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
  • BACKGROUND
Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
IHC-P, E
Primary Accession O95972
Other Accession NP_005439, 257743454
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype IgG
Calculated MW 43 kDa
Application Notes BMP15 antibody can be used for detection of BMP15 by Western blot at 1 - 2 µg/mL.
Additional Information
Gene ID 9210
Target/Specificity BMP15;
Reconstitution & Storage BMP15 antibody can be stored at 4℃ for three months and -20℃, stable for up to one year.
PrecautionsBMP15 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name BMP15
Synonyms GDF9B
Function May be involved in follicular development. Oocyte- specific growth/differentiation factor that stimulates folliculogenesis and granulosa cell (GC) growth.
Cellular Location Secreted.
Research Areas
Citations (0)

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Background

BMP15 Antibody: BMP15, or GDF9B is a member of the bone morphogenetic protein family which is part of the transforming growth factor-beta superfamily that are involved in embryonic development and adult tissue homeostasis. BMP15 is expressed exclusively in the oocyte. It is an oocyte-specific growth/differentiation factor that may be involved in oocyte maturation and follicular development. Defects in BMP15 are the cause of ovarian dysgenesis type 2. BMP15 could be used as an oogenesis marker to track human amniotic fluid stem cells differentiation into the oocyte-like cells.

References

Massague J. The transforming growth factor-beta family. Ann. Rev. Cell. Biol. 1990; 6:597-641
Aaltonen J, Laitinen MP, Vuojolainen K, et al. Human growth differentiation factor 9 (GDF-9) and its novel homolog GDF-9B are expressed in oocytes during early foliculogenesis. J. Clin. Endocrinol. Metab. 1999; 84:2744-50.
Laitinen M, Vuojolainen K, Jaatinen R, et al. A novel growth differentiation factor-9 (GDF-9) related factor is coexpressed with GDF-9 in mouse oocytes during folliculogenesis. Mech. Dev. 1998; 78:135-40.
Galloway SM, Gregan SM, Wilson T et al. Bmp15 mutations and ovarian function. Mol. Cell Endocrinol. 2002; 191:15-8

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$ 310.00
Cat# ASC10739
Size:
Quantity:
(40 western blots)
Availability: 5-7days
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