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NIPSNAP2 Antibody

     
  • WB - NIPSNAP2 Antibody ASC10819
    Western blot analysis of NIPSNAP2 in human skeletal muscle tissue lysate with NIPSNAP2 antibody at (A) 1 and (B) 2 µg/mL.
    detail
  • IHC - NIPSNAP2 Antibody ASC10819
    Immunohistochemistry of NIPSNAP2 in mouse skeletal muscle tissue with NIPSNAP2 antibody at 2.5 µg/mL.
    detail
  • SPECIFICATION
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P, E
Primary Accession O75323
Other Accession O75323, 17380133
Reactivity Human, Mouse, Rat
Host Rabbit
Clonality Polyclonal
Isotype IgG
Calculated MW 33743 Da
Application Notes NIPSNAP2 antibody can be used for detection of NIPSNAP2 by Western blot at 1 - 2 µg/mL. Antibody can also be used for immunohistochemistry starting at 2.5 µg/mL.
Additional Information
Gene ID 2631
Target/Specificity GBAS;
Reconstitution & Storage NIPSNAP2 antibody can be stored at 4℃ for three months and -20℃, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
PrecautionsNIPSNAP2 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name NIPSNAP2 (HGNC:4179)
Synonyms GBAS
Function May act as a positive regulator of L-type calcium channels.
Cellular Location Cytoplasm {ECO:0000250|UniProtKB:O55126}. Mitochondrion outer membrane
Tissue Location Widely expressed. Most abundant in heart and skeletal muscle
Research Areas
Citations (0)
citation

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Background

NIPSNAP2 Antibody: The NIPSNAP proteins comprise a family of evolutionarily well-conserved proteins with strong sequence similarity to the central portion of a protein encoded by C. elegans chromosome III between a 4-nitrophenylphosphatase (NIP) domain and non-neuronal SNAP25-like protein. NIPSNAP2, a novel gene encoding a protein with tyrosine phosphorylation sites and a transmembrane domain, is co-amplified with EGFR in approximately 40% of glioblastomas, the most common and malignant form of central nervous system tumors. It is widely expressed and most abundant in heart and skeletal muscle. NIPSNAP proteins have been suggested to be important in vesicular transport. NIPSNAP2 antibody is predicted to not cross-react with any other members of the NIPSNAP protein family.

References

Seroussi E, Pan HQ, Kedra D, et al. Characterization of the human NIPSNAP1 gene from 22q12: a member of a novel gene family. Gene1998; 212:13-20.
Wang X-Y, Smith DI, Liu W, et al. GBAS, a novel gene encoding a protein with tyrosine phosphorylation sites and a transmembrane domain, is co-amplified with EGFR. Genomics1998; 49:448-51.

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$ 379.00
Cat# ASC10819
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