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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   MTCH2 Antibody   

MTCH2 Antibody

  • WB - MTCH2 Antibody ASC10861
    Western blot analysis of MTCH2 in 293 cell lysate with MTCH2 antibody at 1 µg/mL.
  • IHC - MTCH2 Antibody ASC10861
    Immunohistochemistry of MTCH2 in mouse kidney tissue with MTCH2 antibody at 5 µg/mL.
  • IF - MTCH2 Antibody ASC10861
    Immunofluorescence of MTCH2 in Mouse Kidney cells with MTCH2 antibody at 20 µg/mL.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q791V5
Other Accession NP_055157, 5815347
Reactivity Human, Mouse
Host Rabbit
Clonality Polyclonal
Isotype IgG
Calculated MW 33499 Da
Application Notes MTCH2 antibody can be used for detection of MTCH2 by Western blot at 1 µg/mL. Antibody can also be used for immunohistochemistry starting at 5 µg/mL. For immunofluorescence start at 20 µg/mL.
Additional Information
Gene ID 56428
Target/Specificity Mtch2;
Reconstitution & Storage MTCH2 antibody can be stored at 4℃ for three months and -20℃, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
PrecautionsMTCH2 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name Mtch2
Function The substrate transported is not yet known. Induces mitochondrial depolarization (By similarity).
Cellular Location Mitochondrion inner membrane; Multi-pass membrane protein
Research Areas
Citations (0)

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MTCH2 Antibody: Apoptosis plays a major role in normal organism development, tissue homeostasis, and removal of damaged cells. Disruption of this process has been implicated in a variety of diseases such as cancer. The Bcl-2 family of proteins is comprised of critical regulators of apoptosis that can be divided into two classes: those that inhibit apoptosis and those that promote cell death. MTCH2 is a member of the mitochondrial carrier protein family that catalyze the exchange of substrates across the inner mitochondrial membrane and is targeted by Bid, a pro-apoptotic Bcl-2 family member, in response to apoptotic signals, suggesting that MTCH2 may play a key role in the mitochondrial apoptosis pathway.


Lockshin RA, Osborne B, and Zakeri Z. Cell death in the third millennium. Cell Death Differ.2000; 7:2-7.
Cory S, Huang DCS, and Adams JM. The Bcl-2 family: roles in cell survival and oncogenesis. Oncogene2003; 22:8590-607.
Heiser D, Labi V, Erlacher M, et al. The Bcl-2 protein family and its role in the development of neoplastic disease. Exp. Geron.2004; 39:1125-35.
Grinberg M, Schwarz M, Zaltsman Y, et al. Mitochondrial carrier homolog 2 is a target of tBID in cells signaled to die by tumor necrosis factor alpha. Mol. Cell. Biol.2005; 25:4579-90.

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$ 310.00
Cat# ASC10861
(40 western blots)
Availability: 5-7days
Bulk Size
Seasonal Special on Bulk Order
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