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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   Transthyretin Antibody   

Transthyretin Antibody

  • WB - Transthyretin Antibody ASC10901
    Western blot analysis of Transthyretin in HepG2 cell lysate with Transthyretin antibody at (A) 1 and (B) 2 µg/mL.
  • IHC - Transthyretin Antibody ASC10901
    Immunohistochemistry of Transthyretin in human lung tissue with Transthyretin antibody at 2.5 µg/mL.
  • IF - Transthyretin Antibody ASC10901
    Immunofluorescence of Transthyretin in human lung tissue with Transthyretin antibody at 20 µg/mL.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P02766
Other Accession P02766, 136464
Reactivity Human, Mouse, Rat
Host Chicken
Clonality Polyclonal
Isotype IgY
Calculated MW Predicted: 16 kDa

Observed: 18 kDa
Application Notes Transthyretin antibody can be used for detection of Transthyretin by Western blot at 1 - 2 µg/mL. Antibody can also be used for immunohistochemistry starting at 2.5 µg/mL. For immunofluorescence start at 20 µg/mL.
Additional Information
Gene ID 7276
Target/Specificity TTR;
Reconstitution & Storage Transthyretin antibody can be stored at 4℃ for three months and -20℃, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
PrecautionsTransthyretin Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name TTR
Synonyms PALB
Function Thyroid hormone-binding protein. Probably transports thyroxine from the bloodstream to the brain.
Cellular Location Secreted. Cytoplasm.
Tissue Location Detected in serum and cerebrospinal fluid (at protein level). Highly expressed in choroid plexus epithelial cells. Detected in retina pigment epithelium and liver
Research Areas
Citations (0)

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Transthyretin Antibody: Transthyretin is a tetrameric carrier protein that transports thyroid hormones in the plasma and cerebrospinal fluid, and retinol (vitamin A) in the plasma. More than 80 different mutations in this gene have been reported; most mutations are related to amyloid deposition, affecting predominantly peripheral nerve and/or the heart. The diseases caused by mutations include familial amyloidotic polyneuropathy, euthyroid hyperthyroxinemia, amyloidotic vitreous opacities, cardiomyopathy, oculoleptomeningeal amyloidosis, meningocerebrovascular amyloidosis, and carpal tunnel syndrome. It has also been suggested that Transthyretin plays an important role in the maintenance of normal cognitive processes during aging, neuropeptide processing and nerve regeneration. It has also been linked to several pathological conditions including Parkinson's disease, schizophrenia, and depression.


Fleming CE, Nunes AF, and Sousa MM. Transthyretin: more than meets the eye. Prog. Neurobiol.2009; 89:266-76.
Fleming CE, Saraiva MJ, and Sousa MM. Transthyretin enhances nerve regeneration. J. Neurochem. 2007; 103:831-9.
Rite I, Arguelles S, Venero JL, et al. Proteomic identification of biomarkers in the cerebrospinal fluid in a rat model of nigrostriatal dopaminergic degeneration. J. Neurosci. Res. 2007; 85:3607-18.

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$ 310.00
Cat# ASC10901
(40 western blots)
Availability: 5-7days
Bulk Size
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