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SLAIN1 Antibody

     
  • IHC - SLAIN1 Antibody ASC11009
    Immunohistochemistry of SLAIN1 in human pancreas with SLAIN1 antibody at 5 µg/mL.
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  • SPECIFICATION
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
IHC-P, E
Primary Accession Q8ND83
Other Accession NP_002456, 338968860
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype IgG
Calculated MW 60595 Da
Application Notes SLAIN1 antibody can be used for detection of SLAIN1 by immunohistochemistry at 5 µg/mL.
Additional Information
Gene ID 122060
Target/Specificity SLAIN1; At least three isoforms of SLAIN1 are known to exist; this antibody will detect only the largest isoform. SLAIN1 antibody is predicted not to cross-react with SLAIN2.
Reconstitution & Storage SLAIN1 antibody can be stored at 4℃ for three months and -20℃, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
PrecautionsSLAIN1 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name SLAIN1
Synonyms C13orf32
Function Microtubule plus-end tracking protein that might be involved in the regulation of cytoplasmic microtubule dynamics, microtubule organization and microtubule elongation.
Cellular Location Cytoplasm, cytoskeleton. Note=Colocalizes with microtubules Detected at the plus end of growing microtubules
Tissue Location Expressed in embryonic stem cells (PubMed:16546155). Expressed in brain (PubMed:21646404)
Research Areas
Citations (0)
citation

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Background

SLAIN1 Antibody: SLAIN1 is a novel stem cell protein that was identified by transciptional profiling of mouse and human embryonic stem cells (ESCs) and is expressed at the stem cell and epiblast stages. Unlike its more widely expressed homolog SLAIN2, SLAIN1 was found to be expressed in the epiblast, nervous system, tailbud and somites of the developing mouse embryo later experiments suggested that SLAIN1 may play a role in the development of the nervous system as well as in the morphogenesis of several embryonic structures.

References

Hirst CE, Ng ES, Azzola L, et al. Transcriptional profiling of mouse and human ES cells identifies SLAIN1, a novel stem cell gene. Dev. Biol. 2006; 293:90-103.
Hirst CE, Lim SM, Pereira LA, et al. Expression from a betageo gene trap in the Slain1 gene locus is predominantly associated with the developing nervous system. Int. J. Dev. Biol. 2010; 54:1383-8.

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$ 379.00
Cat# ASC11009
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