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SYNGR1 Antibody

  • WB - SYNGR1 Antibody ASC11046
    Western blot analysis of SYNGR1 in rat brain tissue lysate with SYNGR1 antibody at 1 µg/mL in (A) the absence and (B) the presence of blocking peptide.
  • IHC - SYNGR1 Antibody ASC11046
    Immunohistochemistry of SYNGR1 in rat brain tissue with SYNGR1 antibody at 2.5 µg/mL.
  • IF - SYNGR1 Antibody ASC11046
    Immunofluorescence of SYNGR1 in rat brain tissue with SYNGR1 antibody at 20 µg/mL.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession O43759
Other Accession CAA05322, 2959866
Reactivity Human, Mouse, Rat
Host Rabbit
Clonality Polyclonal
Isotype IgG
Calculated MW 25456 Da
Application Notes SYNGR1 antibody can be used for detection of SYNGR1 by Western blot at 1 µg/mL. Antibody can also be used for immunohistochemistry starting at 2.5 µg/mL. For immunofluorescence start at 20 µg/mL.
Additional Information
Gene ID 9145
Target/Specificity SYNGR1;
Reconstitution & Storage SYNGR1 antibody can be stored at 4℃ for three months and -20℃, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
PrecautionsSYNGR1 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Function Involved in the regulation of short-term and long-term synaptic plasticity.
Cellular Location Membrane; Multi-pass membrane protein Melanosome. Cell junction, synapse. Note=Identified by mass spectrometry in melanosome fractions from stage I to stage IV
Research Areas
Citations (0)

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SYNGR1 Antibody: Synaptogyrins comprise a family of tyrosine-phosphorylated membrane proteins with two neuronal (SYNGR1 and SYNGR3) and one ubiquitous (SYNGR2) members. SYNGR1 and -3 are synaptic vesicle proteins, residing in some cases on the same synaptic vesicle, and are thought to be involved in the regulation of neurotransmitter release. SYNGR2, by contrast, is absent from synaptic vesicles. The role and localization of a fourth synaptogyrin, SYNGR4, is unclear. The gene for SYNGR1is located at chromosome 22q13, a region linked to schizophrenia; however, there is mixed evidence suggesting that mutations in SYNGR1 might be associated with schizophrenia.


Kedra D, Pan HQ, Seroussi E, et al. Characterization of the human synaptogyrin gene family. Hum. Genet.1998; 103:131-41.
Egaña LA, Cuevas RA, Baust TB, et al. Physical and functional interaction between the dopamine transporter and the synaptic vesicle protein synaptogyrin-3. J. Neurosci.2009; 29:4592-604.
Cheng MC and Chen CH. Identification of rare mutations of synaptogyrin 1 gene in patients with schizophrenia. J. Psychiatr. Res.2007; 41:1027-31.
Wang Y, Yu L, Zhao T, et al. No association between bipolar disorder and syngr1 or synapsin II polymorphisms in the Han Chinese population. Psychiatry Res.2009; 169:167-8.

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$ 310.00
Cat# ASC11046
(40 western blots)
Availability: 5-7days
Bulk Size
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