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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   LRRC19 Antibody   

LRRC19 Antibody

  • WB - LRRC19 Antibody ASC11084
    Western blot analysis of LRRC19 in K562 cell lysate with LRRC19 antibody at 1 µg/mL.
  • ICC - LRRC19 Antibody ASC11084
    Immunocytochemistry of LRCC19 in K562 cells with LRCC19 antibody at 2.5 µg/mL.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q9H756
Other Accession NP_075052, 12597641
Reactivity Human, Mouse
Host Rabbit
Clonality Polyclonal
Isotype IgG
Calculated MW 42334 Da
Application Notes LRRC19 antibody can be used for detection of LRRC19 by Western blot at 1 µg/mL. Antibody can also be used for immunocytochemistry starting at 2.5 µg/mL. For immunofluorescence start at 20 µg/mL.
Additional Information
Gene ID 64922
Target/Specificity LRRC19;
Reconstitution & Storage LRRC19 antibody can be stored at 4℃ for three months and -20℃, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
PrecautionsLRRC19 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name LRRC19
Cellular Location Membrane; Single-pass type I membrane protein
Research Areas
Citations (0)

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LRRC19 Antibody: LRRC19 is a member of the extracellular leucine-rich repeat superfamily, a family of proteins that are thought to have diverse functions such as cell adhesion, signaling, and innate immunity. LRRC19 is closely related to the Toll-like receptors (TLRs), especially TLR3. LRRC19 does not contain a cytoplasmic Toll/IL-1 receptor (TIR) domain, but can activate NF-κB and induce the production of proinflammatory cytokines after stimulation with the TLR3 and other TLR ligands, suggesting that LRRC19 may play a role in the recognition and the response to certain pathogenic microorganisms. LRRC19 has also been suggested to be a potential biomarker for pancreatic tumor sensitivity to the anti-cancer, small molecule Src inhibitor AZD0530.


Dolan J, Walshe K, Alsbury S, et al. The extracellular leucine-rich repeat superfamily: a comparative survey and analysis of evolutionary relationships and expression patterns. BMC Genomics2007; 8:320.
Chai L, Dai L, Che Y, et al. LRRC19, a novel member of the leucine-rich repeat protein family, activates NF-kB and induces expression of proinflammatory cytokines. Biochem. Biophys. Res. Comm.2009; 388:543-8.
Rajeshkumar NV, Tan AC, De Oliveira E, et al. Antitumor effects and biomarkers of activity of AZD0530, a Src inhibitor, in pancreatic cancer. Clin. Cancer Res.2009; 15:4138-46.

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$ 330.00
Cat# ASC11084
Availability: 5-7days
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