|Application ||WB, IF, ICC, E|
|Other Accession||NP_065199, 10092689|
|Reactivity||Human, Mouse, Rat|
|Calculated MW||10449 Da|
|Application Notes||LYRM2 antibody can be used for detection of LYRM2 by Western blot at 1 - 2 µg/mL. Antibody can also be used for immunocytochemistry starting at 20 µg/mL. For immunofluorescence start at 20 µg/mL.|
|Reconstitution & Storage||LYRM2 antibody can be stored at 4℃ for three months and -20℃, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.|
|Precautions||LYRM2 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
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Provided below are standard protocols that you may find useful for product applications.
LYRM2 Antibody: The Lyr motif found in the LYR-motif containing protein family is similar to that found in the sacchromyces cerevisiae protein ISD11, an iron-sulfur protein in the mitochondria that is thought to play a role in iron homeostasis. No known function has been assigned to LYRM2, although LYRM1 is thought to be involved in preadipocyte progression and LYRM3 has been suggested to be a candidate gene for the branchio-oto-renal (BOR) syndrome.
Shi Y, Ghosh MC, Tong WH, et al. Human ISD11 is essential for both iron-sulfur cluster assembly and maintenance of normal cellular iron homeostasis. Hum. Mol. Genet.2009; 18:3014-25.
Qiu J, Gao CL, Zhang M, et al. LYRM1, a novel gene promotes proliferation and inhibits apoptosis of preadipocytes. Eur. J. Endocrinol.2009; 160:177-84.
Lin X, Wells DE, Kimberling WJ, et al. Human NDUFB9 gene: genomic organization and a possible candidate gene associated with deafness disorder mapped to chromosome 8q1 Hum. Heredity1999; 49:75-80.
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