|Application ||WB, IHC-P, IF, E|
|Other Accession||Q9Y6M9, 8134589|
|Reactivity||Human, Mouse, Rat|
|Calculated MW||21831 Da|
|Application Notes||LYRM3 antibody can be used for detection of LYRM3 by Western blot at 1 - 2 µg/mL. Antibody can also be used for immunohistochemistry starting at 5 µg/mL. For immunofluorescence start at 20 µg/mL.|
|Reconstitution & Storage||LYRM3 antibody can be stored at 4℃ for three months and -20℃, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.|
|Precautions||LYRM3 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed to be not involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.|
|Cellular Location||Mitochondrion inner membrane; Peripheral membrane protein; Matrix side|
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Provided below are standard protocols that you may find useful for product applications.
LYRM3 Antibody: LYRM3, also known as NADH dehydrogenase (ubiquinone) 1 beta subcomplex 9 (NDUFB9), is a ubiquitously expressed LYR-motif containing protein. It has been suggested to be a candidate gene for the branchio-oto-renal (BOR) syndrome, which is characterized by branchial and renal abnormalities and heredity deafness disorders. Other than its LYR-motif, LYRM3 appears to have no functional or structural relationship to either LYRM1 or LYRM2.
Lin X, Wells DE, Kimberling WJ, et al. Human NDUFB9 gene: genomic organization and a possible candidate gene associated with deafness disorder mapped to chromosome 8q13. Hum. Heredity1999; 49:75-80.
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