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CCDC69 Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, IHC-P, IF, E |
|---|---|
| Primary Accession | A6NI79 |
| Other Accession | NP_056436, 45935391 |
| Reactivity | Human, Mouse, Rat |
| Host | Chicken |
| Clonality | Polyclonal |
| Isotype | IgY |
| Calculated MW | 34796 Da |
| Application Notes | CCDC69 antibody can be used for detection of CCDC69 by Western blot at 1 µg/mL. Antibody can also be used for immunohistochemistry starting at 5 µg/mL. For immunofluorescence start at 20 µg/mL. |
| Gene ID | 26112 |
|---|---|
| Target/Specificity | CCDC69; |
| Reconstitution & Storage | CCDC69 antibody can be stored at 4℃ for three months and -20℃, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures. |
| Precautions | CCDC69 Antibody is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | CCDC69 (HGNC:24487) |
|---|---|
| Function | May act as a scaffold to regulate the recruitment and assembly of spindle midzone components. Required for the localization of AURKB and PLK1 to the spindle midzone. |
| Cellular Location | Cytoplasm, cytoskeleton, spindle. Midbody Note=During early anaphase, localizes along overlapping interpolar microtubules between the separating chromosomes. During late anaphase, localizes to the center of spindle midzone. Concentrated at the midbody during telophase. |
| Tissue Location | Highly expressed in duodenum, esophagus, pancreas, prostate, salivary gland, thymus and urinary bladder |
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Provided below are standard protocols that you may find useful for product applications.
Background
CCDC69 Antibody: The coiled-coil domain is a common protein motif that is often involved in protein oligomerization and is found in proteins such as transcription factors and intermediate filaments. The CCDC47 gene maps to chromosome 5 at 5q33.1. Little is known about this protein.
References
Steinmetz MO, Jelesarov I, Matousek WM, et al. Molecular basis of coiled-coil formation. Proc. Natl. Acad. Sci. USA2007; 104:7062-7.
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