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VENTX Antibody

  • WB - VENTX Antibody ASC11175
    Western blot analysis of VENTX in mouse brain tissue lysate with VENTX antibody at (A) 1 and (B) 2 µg/mL.
  • IHC - VENTX Antibody ASC11175
    Immunohistochemistry of VENTX in rat brain tissue with VENTX antibody at 5 µg/mL.
  • IF - VENTX Antibody ASC11175
    Immunofluorescence of VENTX in rat brain tissue with VENTX antibody at 20 µg/mL.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession O95231
Other Accession NP_055283, 7657180
Reactivity Human, Mouse, Rat
Host Rabbit
Clonality Polyclonal
Isotype IgG
Calculated MW 27552 Da
Application Notes VENTX antibody can be used for detection of VENTX by Western blot at 1 - 2 µg/mL. Antibody can also be used for immunohistochemistry starting at 5 µg/mL.
Additional Information
Gene ID 27287
Target/Specificity VENTX;
Reconstitution & Storage VENTX antibody can be stored at 4℃ for three months and -20℃, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
PrecautionsVENTX Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Synonyms HPX42B, VENTX2
Function May be involved in ventralization.
Cellular Location Nucleus.
Tissue Location Expressed in bone marrow of patients recovering from chemotherapy. Also expressed in an erythroleukemia cell line.
Citations (0)

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VENTX Antibody: Lymphoid-enhancing factor/T-cell factors (LEF1/TCF) are a high-mobility group of transcriptional factors that play essential roles in cell fate determination during early embryogenesis and ontogenesis. VENTX is a member of the Vent family of homeodomain proteins. It is a novel LEF/TCF-associated transcriptional modulator. VENTX is predominately expressed in hematopoietic cells. VENTX may function as a transcriptional repressor and be involved in mesodermal patterning and hemapoietic stem cell maintenance, and has been suggested to have a potential role in the hematopoietic malignancies.


Reya T and Clevers H. Wnt signalling in stem cells and cancer. Nature2005; 434:843-50.
Moretti PA, Davidson AJ, Baker E, et al. Molecular cloning of a human Vent-like homeobox gene. Genomics2001; 76:21-9.
Gao H, Le Y, Wu X, et al. VentX, a novel lymphoid-enhancing factor/T-cell factor-associated transcription repressor, is a putative tumor suppressor. Cancer Res.2010; 70:202-11.
Shtutman M, Zhurinsky J, Simcha I, et al. The cyclin D1 gene is a target of the β-catenin/LEF-1 pathway. Proc. Natl. Acad. Sci. USA1999; 96:5522-7.

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$ 310.00
Cat# ASC11175
(40 western blots)
Availability: 5-7days
Bulk Size
Seasonal Special on Bulk Order
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