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>   home   >   Products   >   Primary Antibodies   >   Immunology   >   NALP8 Antibody   

NALP8 Antibody

  • WB - NALP8 Antibody ASC11197
    Western blot analysis of NALP8 in human colon tissue lysate with NALP8 antibody at 1 µg/mL in (A) the absence and (B) the presence of blocking peptide.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q86W28
Other Accession NP_789781, 33667040
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype IgG
Calculated MW 119430 Da
Application Notes NALP8 antibody can be used for detection of NALP8 by Western blot at 1 µg/mL.
Additional Information
Gene ID 126205
Target/Specificity NLRP8;
Reconstitution & Storage NALP8 antibody can be stored at 4℃ for three months and -20℃, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
PrecautionsNALP8 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name NLRP8
Synonyms NALP8, NOD16, PAN4
Function Involved in inflammation.
Cellular Location Cytoplasm.
Research Areas
Citations (0)

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NALP8 Antibody: NALP proteins are cytoplasmic proteins that form a subfamily within the larger CATERPILLER family and are thought to play a crucial role in cell proliferation and reproduction. Like all other NALP family members, NALP8 has a C-terminal leucine-rich repeat (LRR) region, an N-terminal Pyrin domain (PYD) followed by a NACHT domain, and a NACHT-associated domain. It maps to chromosome 19q13.42 and is thought to be expressed in testis and ovary, suggesting that NALP8 may be involved in reproduction. Surprisingly, NALP8 seems to be universal in mammals except for rodents, suggesting that the gene may have been lost during evolution.


Tschopp J, Martinon F, and Burns K. NALPs: a novel protein family involved in inflammation. Nat. Rev. Mol. Cell Biol.2003; 4:95-104.
Tian X, Pascal G, and Monget P. Evolution and functional divergence of NLRP genes in mammalian reproductive system. BMC Evol. Biol.2009; 9:202.
Ponsuksili P, Brunner RM, Goldammer T, et al. Bovine NALP5, NALP8, and NALP9 genes: assignment to a QTL region and the expression in adult tissues, oocytes, and preimplantation embryos. Biol. Reprod.2006; 74:577-84.

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$ 310.00
Cat# ASC11197
(40 western blots)
Availability: 5-7days
Bulk Size
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