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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   LMBRD1 Antibody   

LMBRD1 Antibody

  • WB - LMBRD1 Antibody ASC11233
    Western blot analysis of LMBRD1 in human brain tissue lysate with LMBRD1 antibody at 1 µg/mL.
  • IHC - LMBRD1 Antibody ASC11233
    Immunohistochemistry of LMBRD1 in human brain tissue with LMBRD1 antibody at 2.5 µg/mL.
  • IF - LMBRD1 Antibody ASC11233
    Immunofluorescence of LMBRD1 in human brain tissue with LMBRD1 antibody at 20 µg/mL.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q9NUN5
Other Accession NP_060838, 261878497
Reactivity Human, Mouse, Rat
Host Rabbit
Clonality Polyclonal
Isotype IgG
Calculated MW 61389 Da
Application Notes LMBRD1 antibody can be used for detection of LMBRD1 by Western blot at 1 µg/mL. Antibody can also be used for immunohistochemistry starting at 2.5 µg/mL. For immunofluorescence start at 20 µg/mL.
Additional Information
Gene ID 55788
Target/Specificity LMBRD1;
Reconstitution & Storage LMBRD1 antibody can be stored at 4℃ for three months and -20℃, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
PrecautionsLMBRD1 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Synonyms C6orf209, NESI
Function Probable lysosomal cobalamin transporter. Required to export cobalamin from lysosomes allowing its conversion to cofactors. Isoform 3 may play a role in the assembly of hepatitis delta virus (HDV).
Cellular Location Lysosome membrane; Multi-pass membrane protein
Tissue Location Isoform 3 is expressed in liver.
Research Areas
Citations (0)

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LMBRD1 Antibody: LMBRD1, also known as NESI (nuclear export signal-interacting protein, is a lysosomal membrane protein that is thought be involved in the transport and metabolism of cobalamin. LMBRD1 was initially identified as interacting with the large form of the hepatitis delta antigen and may be required for the nucleocytoplasmic shuttling of the hepatitis delta virus. Mutations in this gene are associated with the vitamin B12 metabolism disorder termed, homocystinuria-megaloblastic anemia complementation type F (cblF).


Gailus S, Hohne W, Gasnier B, et al. Insights into lysosomal cobalamin trafficking: lessons learned from cblF disease. J. Mol. Med.2010; 88:459-66.
Wang Y-S, Chang SC, Huang C, et al. Novel nuclear export signal-interacting protein, NESI, critical for the assembly of hepatitis delta virus. J. Virol.2005; 79:8113-20.

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$ 310.00
Cat# ASC11233
(40 western blots)
Availability: 5-7days
Bulk Size
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