|Application ||WB, IHC-P, IF, E|
|Other Accession||NP_064610, 55742730|
|Reactivity||Human, Mouse, Rat|
|Calculated MW||102671 Da|
|Application Notes||STOX2 antibody can be used for detection of STOX2 by Western blot at 1 µg/mL. Antibody can also be used for immunohistochemistry starting at 2.5 µg/mL. For immunofluorescence start at 20 µg/mL.|
|Reconstitution & Storage||STOX2 antibody can be stored at 4℃ for three months and -20℃, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.|
|Precautions||STOX2 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
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Provided below are standard protocols that you may find useful for product applications.
STOX2 Antibody: The Storkhead box protein 2 (STOX2) is the only known paralog to STOX1, a winged-helix domain containing transcription factor believed to play a role in the differentiation of stem cells. STOX2 has been suggested to be part of a molecular profile unique to stem cells, and its mRNA may be part of a transcriptional profile observed with increased inflammatory response to air pollutants. Decreased STOX2 expression levels in decidua are also correlated with preeclampsia, suggesting STOX2 may play a role in the pathophysiology of preeclampsia.
van Dijk M, van Bezu J, Chim SS, et al. Maternal segregation of the Dutch preeclampsia locus at 10q22 with a new member of the winged helix gene family. Nat. Genet.2005; 37:514-9.
Kivinen K, Peterson H, Hiltunen L, et al. Evaluation of STOX1 as a preeclampsia candidate gene in a population-wide sample. Eur. J. Hum. Genet.2007; 15:494-7.
Thomas S, Thomas M, Wincker P, et al. Human neural crest cells display molecular and phenotypic hallmarks of stem cells. Hum. Mol. Genet.2008; 17:3411-25.
Fedulov AV, Leme A, Yang Z, et al. Pulmonary exposure to particles during pregnancy causes increased neonatal asthma susceptibility. Am. J. Respir. Cell Mol. Biol.2008; 38:57-67.
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