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ZIP6 Antibody

  • WB - ZIP6 Antibody ASC11247
    Western blot analysis of ZIP6 in mouse lung tissue lysate with ZIP6 antibody at 1 µg/mL.
  • IHC - ZIP6 Antibody ASC11247
    Immunohistochemistry of ZIP6 in mouse lung tissue with ZIP6 antibody at 5 µg/mL.
  • IF - ZIP6 Antibody ASC11247
    Immunofluorescence of ZIP6 in mouse lung tissue with ZIP6 antibody at 20 µg/mL.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q13433
Other Accession NP_001092876, 153252214
Reactivity Human, Mouse
Host Rabbit
Clonality Polyclonal
Isotype IgG
Calculated MW 85047 Da
Application Notes ZIP6 antibody can be used for detection of ZIP6 by Western blot at 1 µg/mL. Antibody can also be used for immunohistochemistry starting at 2.5 µg/mL. For immunofluorescence start at 20 µg/mL.
Additional Information
Gene ID 25800
Target/Specificity SLC39A6;
Reconstitution & Storage ZIP6 antibody can be stored at 4℃ for three months and -20℃, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
PrecautionsZIP6 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name SLC39A6
Synonyms LIV1, ZIP6
Function May act as a zinc-influx transporter.
Cellular Location Cell membrane; Multi-pass membrane protein
Tissue Location Highly expressed in the breast, prostate, placenta, kidney, pituitary and corpus callosum. Weakly expressed in heart and intestine. Also highly expressed in cells derived from an adenocarcinoma of the cervix and lung carcinoma
Research Areas
Citations (0)

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ZIP6 Antibody: The zinc transporter ZIP6, also known as SLC39A6, is a member of a family of divalent ion transporters. Zinc is an essential ion for cells and plays significant roles in the growth, development, and differentiation. ZIP6 was initially identified as LIV-1, an estrogen-regulated gene that has been implicated in metastatic breast cancer. Elevated ZIP6 expression has also been reported in human cervical cancer and the HeLa cell line; down-regulation of ZIP6 expression in HeLa by RNAi inhibited cell proliferation, colony formation, migration and invasiveness, as well as decreasing Snail and Slug levels, suggesting ZIP6 plays a regulatory role on the ERK1/2-Snail/Slug pathway.


Dufner-Beattie J, Langmade SJ, Wang F, et al. Structure, function, and regulation of a subfamily of mouse zinc transporter genes. J. Biol. Chem.2003; 278:50142-50.
Eide DJ. The SLC39 family of metal ion transporters. Pflugers Arch.2004; 447:796-800.
Taylor KM and Nicohlson RI. The LZT proteins; the LIV-1 subfamily of zinc transporters. Biochim. Biophys. Acta.2003; 1611:16-30.
Taylor KM. LIV-1 breast cancer protein belongs to new family of histidine-rich membrane proteins with potential to control intracellular ZN2+ homeostasis. IUBMB Life2000; 49:249-53.

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$ 310.00
Cat# ASC11247
(40 western blots)
Availability: 5-7days
Bulk Size
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