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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   ZIP8 Antibody   

ZIP8 Antibody

  • WB - ZIP8 Antibody ASC11249
    Western blot analysis of ZIP8 in human spleen tissue lysate with ZIP8 antibody at (A) 1 and (B) 2 µg/mL.
  • IHC - ZIP8 Antibody ASC11249
    Immunohistochemistry of ZIP8 in human spleen tissue with ZIP8 antibody at 5 µg/mL.
  • IF - ZIP8 Antibody ASC11249
    Immunofluorescence of ZIP8 in human spleen tissue with ZIP8 antibody at 20 µg/mL.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q9C0K1
Other Accession NP_071437, 205830403
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype IgG
Calculated MW 49631 Da
Application Notes ZIP8 antibody can be used for detection of ZIP8 by Western blot at 1 - 2 µg/mL. Antibody can also be used for immunohistochemistry starting at 5 µg/mL. For immunofluorescence start at 20 µg/mL.
Additional Information
Gene ID 64116
Target/Specificity Slc39a8; ZIP8 antibody is predicted to not cross-react with other ZIP family members.
Reconstitution & Storage ZIP8 antibody can be stored at 4℃ for three months and -20℃, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
PrecautionsZIP8 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name SLC39A8
Synonyms BIGM103, ZIP8
Function Acts as a zinc-influx transporter.
Cellular Location Membrane; Multi-pass membrane protein. Note=Associated with the lysosomal/endosomal compartment following transfection
Tissue Location Expressed in thymus, placenta, lung, liver, pancreas and, to a lower extent, in spleen, testis, ovary, small intestine, colon, leukocyte, heart. Highest expression is observed in pancreas.
Research Areas
Citations (0)

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ZIP8 Antibody: The zinc transporter ZIP8, also known as SLC39A9, is a member of a family of divalent ion transporters. Zinc is an essential ion for cells and plays significant roles in the growth, development, and differentiation. The zinc transporter family is divided into four subfamilies (I, II, LIV-1 and gufA). ZIP8 is glycosylated and located at the plasma membrane and mitochondria. It has been identified as the transporter responsible for transport of the toxic Cadmium cation. ZIP8 has also been suggested to play a role in the regulation of interferon-gamma expression in activated human T cells.


Dufner-Beattie J, Langmade SJ, Wang F, et al. Structure, function, and regulation of a subfamily of mouse zinc transporter genes. J. Biol. Chem.2003; 278:50142-50.
Eide DJ. The SLC39 family of metal ion transporters. Pflugers Arch.2004; 447:796-800.
Taylor KM and Nicohlson RI. The LZT proteins; the LIV-1 subfamily of zinc transporters. Biochim. Biophys. Acta.2003; 1611:16-30.
Dalton TP, He L, Wang B, et al. Identification of mouse SLC39A8 as the transporter responsible for cadmium-induced toxicity in the testis. Proc. Natl. Acad. Sci. USA2005; 102:3401-6.

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$ 310.00
Cat# ASC11249
(40 western blots)
Availability: 5-7days
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