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ZBTB5 Antibody

  • WB - ZBTB5 Antibody ASC11262
    Western blot analysis of ZBTB5 in mouse brain tissue lysate with ZBTB5 antibody at (A) 1 and (B) 2 µg/mL.
  • IHC - ZBTB5 Antibody ASC11262
    Immunohistochemistry of ZBTB5 in human brain tissue with ZBTB5 antibody at 2.5 µg/mL.
  • IF - ZBTB5 Antibody ASC11262
    Immunofluorescence of ZBTB5 in human brain tissue with ZBTB5 antibody at 20 µg/mL.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession O15062
Other Accession NP_055687, 7662074
Reactivity Human, Mouse, Rat
Host Rabbit
Clonality Polyclonal
Isotype IgG
Calculated MW 74278 Da
Application Notes ZTBT5 antibody can be used for detection of ZTBT5 by Western blot at 1 - 2 µg/mL. Antibody can also be used for immunohistochemistry starting at 2.5 µg/mL. For immunofluorescence start at 20 µg/mL.
Additional Information
Gene ID 9925
Target/Specificity ZBTB5; At least two isoforms of ZBTB5 are known to exist; this antibody will recognize both isoforms. This antibody is predicted to not cross-react with other ZBTB protein family members.
Reconstitution & Storage ZBTB5 antibody can be stored at 4℃ for three months and -20℃, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
PrecautionsZBTB5 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name ZBTB5
Synonyms KIAA0354
Function May be involved in transcriptional regulation.
Cellular Location Nucleus.
Citations (0)

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ZBTB5 Antibody: The ZBTB family of proteins is comprised of diverse zinc finger proteins that also contain a BTB (BR-C, ttk and bab) domain. ZBTB5 was identified though sequence analysis as a POZ domain Kruppel-like zinc finger (POK) protein. Further experiments indicated that it binds DNA and can directly repress transcription of the cell cycle arrest gene p21. ZBTB5 can also interact with co-repressor histone deacetylase complexes such as BCoR, NCoR, and SMRT via its POZ domain, resulting in deacetylation of histones Ac-H3 and Ac-H4 at the proximal promoter. ZBTB5 stimulates both cell proliferation and cell cycle progression, suggesting that it may act as a potential proto-oncogene.


Strausberg RL, Feingold EA, Grouse LH, et al. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Proc. Natl. Acad. Sci. USA2002; 99:16899-903.
Koh D, Choi W, Jeon B, et al. A novel POK family transcription factor, ZBTB5, represses transcription of p21CIP1 gene. J. Biol. Chem.2009; 284:19856-66.

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$ 310.00
Cat# ASC11262
(40 western blots)
Availability: 5-7days
Bulk Size
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