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MEIG1 Antibody

  • WB - MEIG1 Antibody ASC11337
    Western blot analysis of MEIG in K562 cell lysate with MEIG antibody at 1 µg/mL in (A) the absence and (B) the presence of blocking peptide.
  • IHC - MEIG1 Antibody ASC11337
    Immunohistochemistry of MEIG1 in rat testis tissue with MEIG1 antibody at 5 µg/mL.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q5JSS6
Other Accession Q5JSS6, 124249370
Reactivity Human, Mouse, Rat
Host Rabbit
Clonality Polyclonal
Isotype IgG
Calculated MW 10795 Da
Application Notes MEIG1 antibody can be used for detection of MEIG1 by Western blot at 1 µg/mL. Antibody can also be used for immunohistochemistry starting at 5 µg/mL.
Additional Information
Gene ID 644890
Target/Specificity MEIG1;
Reconstitution & Storage MEIG1 antibody can be stored at 4℃ for three months and -20℃, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
PrecautionsMEIG1 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name MEIG1
Function Essential for spermiogenesis.
Citations (0)

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MEIG1 Antibody: MEIG1, a murine gene first identified as a testis specific gene, is a chromosome/chromatin-binding protein initially expressed during meiosis but retained in the germ cell nucleus throughout later stages of spermatogenesis. MEIG1 is a highly conserved basal metazoan gene that is indispensable for mouse spermatogenesis. It is important for normal meiotic differentiation and absolutely crucial for terminal differentiation of spermatozoa. MEIG1 encodes two alternative transcripts, designated 2a2 and 11a2, both of which encode for a common ORF but differing in their 5' untranslated region (5'UTR) due to alternative promoters.


Don J and Wolgemuth DJ. Identification and characterization of the regulated pattern of expression of a novel mouse gene, meg1, during the meiotic cell cycle. Cell Growth Differ. 1992; 3:495-505
Salzberg Y, Eldar T, Karminsky OD, et al. Meig1 deficiency causes a severe defect in mouse spermatogenesis. Dev. Biol. 2010; 338:158-67.
Zhang Z, Shen X, Gude DR, et al. MEIG1 is essential for spermiogenesis in mice. Proc. Natl. Acad. Sci. USA 2009; 106:17055-60.
Ever L, Steiner R, Shalom S, et al. Two alternatively spliced Meig1 messenger RNA species are differentially expressed in the somatic and in the germ-cell compartments of the testis. Cell Growth Differ. 1999; 10:19-26.

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$ 330.00
Cat# ASC11337
Availability: 5-7days
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