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KCNK13 Antibody

  • WB - KCNK13 Antibody ASC11354
    Western blot analysis of KCNK13 in rat brain tissue lysate with KCNK13 antibody at 0.5 µg/mL in (A) the absence and (B) the presence of blocking peptide.
  • IHC - KCNK13 Antibody ASC11354
    Immunohistochemistry of KCNK13 in human brain tissue with KCNK13 antibody at 5 µg/mL.
  • IF - KCNK13 Antibody ASC11354
    Immunofluorescence of KCNK13 in human brain tissue with KCNK13 antibody at 20 µg/mL.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q9HB14
Other Accession NP_071337, 16306555
Reactivity Human, Mouse, Rat
Host Rabbit
Clonality Polyclonal
Isotype IgG
Calculated MW 45391 Da
Application Notes KCNK13 antibody can be used for detection of KCNK13 by Western blot at 0.5 µg/mL. Antibody can also be used for immunohistochemistry starting at 5 µg/mL. For immunofluorescence start at 20 µg/mL.
Additional Information
Gene ID 56659
Target/Specificity KCNK13; KCNK13 antibody is predicted to not cross-react with other KCNK protein family members.
Reconstitution & Storage KCNK13 antibody can be stored at 4℃ for three months and -20℃, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
PrecautionsKCNK13 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name KCNK13
Function Potassium channel displaying weak inward rectification in symmetrical K(+) solution.
Cellular Location Membrane; Multi-pass membrane protein
Research Areas
Citations (0)

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KCNK13 Antibody: The closely related proteins KCNK13 and KCNK12 (also known as THIK1 and 2) are the first two members of a novel two pore-forming P domains K+ channels subfamily. The pore loop domain, a highly conserved region common to all potassium channels, is involved in determining potassium ion selectivity. Members of this family are all characterized by four transmembrane domains and may function to help influence the resting membrane potential of cells. KCNK13 is expressed mainly in the brain, but is also observed in kidneys. KCNK13 has been suggested to be a candidate for the Cs+-permeable K+ channel activated by GABA(B) receptors.


Rajan S, Wischmeyer E, Karschin C, et al. THIK-1 and THIK-2, a novel subfamily of tandem pore domain K+ channels. J. Biol. Chem. 2001; 276:7302-11.
Jezzini SH and Moroz LL. Identification and distribution of a twopore domain potassium channel in the CNS of Aplysia californica. Brain Res. Mol. Brain Res. 2004; 127:27-38.
Theilig F, Goranova I, Hirsch JR, et al. Cellular localization of THIK-1 (K(2P)13.1) and THIK-2 (K(2P)12.1) K channels in the mammalian kidney. Cell Physiol. Biochem. 2008; 21:63-74
Ishii H, Nakajo K, Yanagawa Y, et al. Identification and characterization of Cs(+)-permeable K(+) channel current in mouse cerebellar Purkinje cells in lobules 9 and 10 evoked by molecular layer stimulation. Eur. J. Neurosci. 2010; 32:736-48

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$ 310.00
Cat# ASC11354
(40 western blots)
Availability: 5-7days
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