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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   FXYD7 Antibody   

FXYD7 Antibody

  • WB - FXYD7 Antibody ASC11369
    Western blot analysis of FXYD7 in human lung tissue lysate with FXYD7 antibody at 1 µg/mL.
  • IHC - FXYD7 Antibody ASC11369
    Immunohistochemistry of FXYD7 in rat lung tissue with FXYD7 antibody at 2.5 µg/mL.
  • IF - FXYD7 Antibody ASC11369
    Immunofluorescence of FXYD4 in rat lung tissue with FXYD4 antibody at 20 µg/mL.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P58549
Other Accession AAH18619, 11612659
Reactivity Human, Mouse, Rat
Host Rabbit
Clonality Polyclonal
Isotype IgG
Calculated MW 8524 Da
Application Notes FXYD7 antibody can be used for detection of FXYD7 by Western blot at 1 µg/mL. Antibody can also be used for immunohistochemistry starting at 2.5 µg/mL. For immunofluorescence start at 20 µg/mL.
Additional Information
Gene ID 53822
Target/Specificity FXYD7; FXYD7 antibody is human, mouse and rat reactive. FXYDY7 antibody is predicted to not react with other members of the FXDY protein family
Reconstitution & Storage FXYD7 antibody can be stored at 4℃ for three months and -20℃, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
PrecautionsFXYD7 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name FXYD7
Cellular Location Membrane; Single-pass membrane protein
Research Areas
Citations (0)

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FXYD7 Antibody: FXYD7 is a member of a family of small membrane proteins that share a 35-amino acid signature sequence domain, beginning with the sequence PFXYD and containing seven invariant and six highly conserved amino acids. The FXYD proteins are tissue-specific regulators of Na, K-ATPase, with FXYD7 initially identified as a brain-specific member. FXYD7 interacts with Na, K-ATPase through its transmembrane domain and is thought to influence the affinity of Na, K-ATPase for external K+ and Na+ ions. Other members of the FXDY family have similar functions: FXYD2 regulates the properties of Na, K-ATPase, while FXYD1 (phospholemman), FXYD3 (MAT-8), FXYD4 (CHIF), and FXYD5 (RIC) have been shown to induce channel activity in experimental expression systems.


Beguin P, Crambert G, Monnet-Tschudi F, et al. FXYD7 is a brain-specific regulator of Na,K-ATPase alpha1-beta isozymes. EMBO J. 2002; 21:3264-73
Crambert G and Geering K. FXYD proteins: new tissue-specific regulators of the ubiquitous Na,K-ATPase. Sci. STKE 2003; 2003 (166):RE1.
Li C, Crambert G, Thuillard D, et al. role of the transmembrane domain of FXDY7 in structural and functional interactions with Na,K-ATPase. J. Biol. Chem. 2005; 280:42738-43.

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$ 330.00
Cat# ASC11369
Availability: 5-7days
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