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ECRG1 Antibody

  • WB - ECRG1 Antibody ASC11385
    Western blot analysis of ECRG1 in mouse liver tissue lysate with ECRG1 antibody at 1 µg/mL in (A) the absence and (B) the presence of blocking peptide.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q6ZMR5
Other Accession Q6ZMR5, 167466250
Reactivity Human, Mouse, Rat
Host Chicken
Clonality Polyclonal
Isotype IgY
Calculated MW 47569 Da
Application Notes ECRG1 antibody can be used for detection of ECRG1 by Western blot at 1 µg/mL.
Additional Information
Gene ID 339967
Target/Specificity TMPRSS11A; At least two isoforms of ECRG1 are known to exist; ECRG1 antibody is predicted to not cross-react with other ECRG family members.
Reconstitution & Storage ECRG1 antibody can be stored at 4℃ for three months and -20℃, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
PrecautionsECRG1 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Synonyms ECRG1, HATL1, HESP
Function Probable serine protease which may play a role in cellular senescence. Overexpression inhibits cell growth and induce G1 cell cycle arrest.
Cellular Location Membrane; Single-pass type II membrane protein
Tissue Location Expressed in esophagus, liver, colon and lung. Down-regulated in esophagus cancers
Research Areas
Citations (0)

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ECRG1 Antibody: Epidermal type-II transmembrane serine protease (ECRG1), also known as TMPRSS11A, is a member of a novel esophageal cancer-related gene family. It is a type-II transmembrane serine protease which may play a role in cellular senescence. It is expressed in esophagus, liver, colon and lung. Overexpression of ECRG1 inhibits cell growth and induces G1 cell cycle arrest. It is down-regulated in esophagus cancers (EC) and might play important roles in the initiation and progression of EC.


Yueying W, Jianbo W, Hailin L, et al. ECRG1, a novel esophageal gene, cloned and identified from human esophagus and its inhibition effect on tumors. Carcinogenesis 2008; 29:157-60.
Zhao N, Wang J, Cui Y, et al. Induction of G1 cell cycle arrest and P15INK4b expression by ECRG1 through interaction with Miz-1. J. Cell Biochem. 2004; 92:65-76
Zhao N, Huang G, Guo L, et al. ECRG1, a novel candidate of tumor suppressor gene in the esophageal carcinoma, triggers a senescent program in NIH3T3 cells. Exp. Biol. Med. 2006; 231:84-90.

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$ 310.00
Cat# ASC11385
(40 western blots)
Availability: 5-7days
Bulk Size
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