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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   MS4A6A Antibody   

MS4A6A Antibody

  • WB - MS4A6A Antibody ASC11403
    Western blot analysis of MS4A6A in 293 cell lysate with MS4A6A antibody at (A) 1 and (B) 2 µg/mL.
  • IHC - MS4A6A Antibody ASC11403
    Immunohistochemistry of MS4A6A in rat brain tissue with MS4A6A antibody at 2.5 µg/mL.
  • IF - MS4A6A Antibody ASC11403
    Immunofluorescence of MS4A6A in rat brain tissue with MS4A6A antibody at 20 µg/mL.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q9H2W1
Other Accession NP_071744, 23238238
Reactivity Human, Mouse, Rat
Host Rabbit
Clonality Polyclonal
Isotype IgG
Calculated MW 26943 Da
Application Notes MS4A6A antibody can be used for detection of MS4A6A by Western blot at 1 - 2 µg/mL. Antibody can also be used for immunohistochemistry starting at 2.5 µg/mL. For immunofluorescence start at 20 µg/mL.
Additional Information
Gene ID 64231
Target/Specificity MS4A6A; At least three isoforms of MS4A6A are known to exist; this antibody will detect the two longer isoforms. MS4A6A antibody is predicted to not cross-react with MS4A family members.
Reconstitution & Storage MS4A6A antibody can be stored at 4℃ for three months and -20℃, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
PrecautionsMS4A6A Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name MS4A6A
Synonyms 4SPAN3, CD20L3, MS4A6
Function May be involved in signal transduction as a component of a multimeric receptor complex.
Cellular Location Membrane; Multi-pass membrane protein.
Tissue Location Variable expression in some B-cell, myelomonocytic, and erythroleukemia cell lines
Research Areas
Citations (0)

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MS4A6A Antibody: The MS4A gene family in humans includes CD20 (MS4A1), FcRbeta (MS4A2), Htm4 (MS4A3), and at least 13 other genes encoding membrane proteins, most having characteristic tetraspanning topology and similar intron/exon splice boundaries. All family members display unique expression patterns among hematopoietic cells and non-lymphoid tissues. The function of MS4A6A has been suggested to be involved in signal transduction as a component of a multimeric receptor complex in Alzheimer's disease and cancer.


Liang Y and Tedder TF. Identification of a CD20-, FcepsilonRIbeta-, and HTm4-related gene family: sixteen new MS4A family members expressed in human and mouse. Genomics 2001; 72:119-27
Ishibashi K, Suzuki M, Sasaki S, et al. Identification of a new multigene four-transmembrane family (MS4A) related to CD20, HTm4 and beta subunit of the high-affinity IgE receptor. Gene 2001; 264:87-93.
Antúnez C, Boada M, Gonzalez-Pérez A, et al. The membrane-spanning 4-domains, subfamily A (MS4A) gene cluster contains a common variant associated with Alzheimer's disease. Genome Med. 2011; 3:33
Hollingworth P, Harold D, Sims R, et al. Common variants at ABCA7, MS4A6A/MS4A4E, EPHA1, CD33 and CD2AP are associated with Alzheimer's disease. Nat. Genet. 2011; 43:429-35.

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$ 310.00
Cat# ASC11403
(40 western blots)
Availability: 5-7days
Bulk Size
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