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LEMD1 Antibody

  • WB - LEMD1 Antibody ASC11405
    Western blot analysis of LEMD1 in A20 cell lysate with LEMD1 antibody at 1 µg/mL in (A) the absence and (B) the presence of blocking peptide.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q68G75
Other Accession Q68G75, 312261248
Reactivity Human, Mouse
Host Rabbit
Clonality Polyclonal
Isotype IgG
Calculated MW 20326 Da
Application Notes LEMD1 antibody can be used for detection of LEMD1 by Western blot at 1 µg/mL.
Additional Information
Gene ID 93273
Target/Specificity LEMD1; At least six isoforms of LEMD1 are known to exist; this antibody will detect the longest isoform. LEMD1 antibody is predicted to not cross-react with LEMD2 and LEMD3.
Reconstitution & Storage LEMD1 antibody can be stored at 4℃ for three months and -20℃, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
PrecautionsLEMD1 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name LEMD1
Cellular Location Membrane; Single-pass membrane protein
Tissue Location Testis-specific. Isoform 6 is detected in 17 of 18 colon cancer tissues examined
Research Areas
Citations (0)

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LEMD1 Antibody: LEMD1 (LEM domain-containing1) is a member of cancer-testis gene family. LEMD1 is normally expressed only in testis. Six alternatively spliced forms of LEMD1 transcripts in normal testis have been identified, but only one of the six was expressed in colorectal cancers. LEMD1 may represent a promising target antigen for immunotherapy of colorectal cancers. In addition, LEMD1 and SPATA19 are putative cancer biomarkers and promising targets for active immunotherapy.


Yuki D, Lin YM, Fujii Y, et al. Isolation of LEM domain-containing 1, a novel testis-specific gene expressed in colorectal cancers. Oncol. Rep. 2004; 12:275-80
Ghafouri-Fard S, Ousati Ashtiani Z, Sabah Golian B, et al. Expression of two testis-specific genes, SPATA19 and LEMD1, in prostate cancer. Arch. Med. Res. 2010; 41:195-200

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$ 310.00
Cat# ASC11405
(40 western blots)
Availability: 5-7days
Bulk Size
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