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FOXD4L1 Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, ICC, E |
|---|---|
| Primary Accession | Q9NU39 |
| Other Accession | NP_036316, 18959276 |
| Reactivity | Human, Mouse |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Calculated MW | 43610 Da |
| Application Notes | FOXD4L1 antibody can be used for detection of FOXD4L1 by Western blot at 1 µg/mL. Antibody can also be used for immunocytochemistry at 10 µg/ml. |
| Gene ID | 200350 |
|---|---|
| Target/Specificity | FOXD4L1; This antibody is predicted to not cross-react with any FOXD4 protein family members |
| Reconstitution & Storage | FOXD4L1 antibody can be stored at 4℃ for three months and -20℃, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures. |
| Precautions | FOXD4L1 Antibody is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | FOXD4L1 |
|---|---|
| Cellular Location | Nucleus {ECO:0000255|PROSITE-ProRule:PRU00089}. |
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Provided below are standard protocols that you may find useful for product applications.
Background
FOXD4L1 Antibody: FOXD4L1, also known as FOXD5, is a member of the forkhead/winged-helix (FOX) family of transcription factors with highly conserved FOX DNA-binding domains. Members of the FOX family of transcription factors are regulators of embryogenesis and is thought to play a role in human cancer. FOXD4L1 is a forkhead transcription factor that functions as both a transcriptional activator and repressor and acts upstream of several other neural transcription factors to maintain neural fate, regulate neural plate patterning, and delay the expression of neural differentiation factors.
References
Jackson BC, Carpenter C, Nebert DW, et al. Update of human and mouse forkhead box (FOX) gene families. Hum. Genomics 2010; 4:345-52.
Yan B, Neilson KM, and Moody SA. Microarray identification of novel downstream targets of FoxD4L1/D5, a critical component of the neural ectodermal transcriptional network. Dev. Dyn. 2010; 239:3467-80.
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