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NKX2-4 Antibody

  • WB - NKX2-4 Antibody ASC11447
    Western blot analysis of NKX2-4 in A20 cell lysate with NKX2-4 antibody at 1 µg/mL in (A) the absence and (B) the presence of blocking peptide.
  • ICC - NKX2-4 Antibody ASC11447
    Immunocytochemistry of NKX2-4 in A20 cells with NKX2-4 antibody at 2.5 µg/mL.
  • IF - NKX2-4 Antibody ASC11447
    Immunofluorescence of NKX2-4 in A20 cells with NKX2-4 antibody at 20 µg/mL.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q9H2Z4
Other Accession NP_149416, 157426823
Reactivity Human, Mouse
Host Rabbit
Clonality Polyclonal
Isotype IgG
Calculated MW 36179 Da
Application Notes NKX2-4 antibody can be used for detection of NKX2-4 by Western blot at 1 µg/mL. Antibody can also be used for immunocytochemistry starting at 2.5 µg/mL. For immunofluorescence start at 20 µg/mL.
Additional Information
Gene ID 644524
Target/Specificity NKX2-4; NKX2-4 antibody is predicted to not cross-react with other NK2 homeobox family members. At least two isoforms of NKX2-4 are known to exist; this antibody will detect both isoforms.
Reconstitution & Storage NKX2-4 antibody can be stored at 4℃ for three months and -20℃, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
PrecautionsNKX2-4 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name NKX2-4
Synonyms NKX2D
Function Probable transcription factor.
Cellular Location Nucleus {ECO:0000255|PROSITE- ProRule:PRU00108}
Citations (0)

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NKX2-4 Antibody: NKX2-4 (NK2 homeobox 4) is a member of a family of transcription factors that are involved in embryonic development and cell fate. NKX2-4 is closely related to NKX2-1 and NKX2-4 and is specifically localized to the ventral diencephalon. Recent experiments in Xenopus have suggested that the homeodomain protein XANF is necessary for the activation of NKX2-4, but does not directly regulate its expression.


Wang CC, Brodnicki T, Copeland NG, et al. Conserved linkage of NK-2 homeobox gene pairs Nkx2-2/2-4 and Nkx2-1/2-9 in mammals. Mamm. Genome 2000; 11:466-8.
Small EM, Vokes SA, Garriock RJ, et al. Developmental expression of the Xenopus Nkx2-1 and Nkx2-4 genes. Mech. Dev. 2000; 96:259-62.
Hill JT, Chao CS, Anderson KR, et al. Nkx2.2 activates the ghrelin promoter in pancreatic islet cells. Mol. Endocrinol. 2010; 381-90.

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$ 310.00
Cat# ASC11447
(40 western blots)
Availability: 5-7days
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