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>   home   >   Products   >   Primary Antibodies   >   Developmental Biology   >   NKX2-6 Antibody   

NKX2-6 Antibody

  • WB - NKX2-6 Antibody ASC11448
    Western blot analysis of NKX2-6 in mouse heart tissue lysate with NKX2-6 antibody at 1 µg/mL in (A) the absence and (B) the presence of blocking peptide.
  • IHC - NKX2-6 Antibody ASC11448
    Immunohistochemistry of NKX2-6 in human spleen tissue with NKX2-6 antibody at 5 µg/mL.
  • IF - NKX2-6 Antibody ASC11448
    Immunofluorescence of NKX-6 in human spleen tissue with NKX2-6 antibody at 20 µg/mL.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession A6NCS4
Other Accession NP_001129743, 343183350
Reactivity Human, Mouse
Host Rabbit
Clonality Polyclonal
Isotype IgG
Calculated MW 32121 Da
Application Notes NKX2-6 antibody can be used for detection of NKX2-6 by Western blot at 1 µg/mL. Antibody can also be used for immunohistochemistry starting at 5 µg/mL. For immunofluorescence start at 5 µg/mL.
Additional Information
Gene ID 137814
Target/Specificity NKX2-6; NKX2-6 antibody is predicted to not cross-react with other NK2 homeobox family members. At least two isoforms of NKX2-6 are known to exist; this antibody will detect both isoforms
Reconstitution & Storage NKX2-6 antibody can be stored at 4℃ for three months and -20℃, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
PrecautionsNKX2-6 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name NKX2-6
Synonyms NKX2F
Function Acts as a transcriptional activator (PubMed:15649947). In conjunction with NKX2-5, may play a role in both pharyngeal and cardiac embryonic development.
Cellular Location Nucleus.
Research Areas
Citations (0)

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NKX2-6 Antibody: NKX2-6 (NK2 homeobox 6) is a member of a family of transcription factors that are involved in embryonic development and cell fate. NKX2-6 is a vertebrate homolog of Drosophila homeobox-containing protein called 'tinman', which has been shown to be essential for development of the heart-like dorsal vessel. In conjunction with related gene, NKX2-5, this gene may play a role in both pharyngeal and cardiac embryonic development. Mutations in this gene are thought to be a cause for some congenital heart abnormalities.


Copeland NG, Jenkins NA, and Harvey RP. The murine homeobox genes Nkx2.3 and Nkx2.6 are located on chromosomes 19 and 14, respectively. Genomics 1994; 22:655-6.
Tanaka M, Kasahara H, Bartunkova S, et al. Vertebrate homologs of tinman and bagpipe: roles of the homeobox genes in cardiovascular development. Dev. Genet. 1998; 22:239-49.
Biben C, Hatzistavrou T, and Harvey RP. Expression of NK-2 class homeobox gene Nkx2-6 in foregut endoderm and heart. Mech. Dev. 1998; 73:125-7
Tanaka M, Schinke M, Liao HS, et al. Nkx2.5 and Nkx2.6, homologs of Drosophila tinman, are required for development of the pharynx. Mol. Cell. Biol. 2001; 21:4391-8.

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$ 310.00
Cat# ASC11448
(40 western blots)
Availability: 5-7days
Bulk Size
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