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YPEL4 Antibody

  • WB - YPEL4 Antibody ASC11459
    Western blot analysis of YPEL4 in SW480 cell lysate with YPEL4 antibody at 1 µg/mL in (A) the absence and (B) the presence of blocking peptide.
  • ICC - YPEL4 Antibody ASC11459
    Immunocytochemistry of YPEL4 in SW480 cells with YPEL4 antibody at 2.5 µg/ml.
  • IF - YPEL4 Antibody ASC11459
    Immunofluorescence of YPEL4 in SW480 cells with YPEL4 antibody at 5 µg/ml.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q96NS1
Other Accession NP_659455, 21450727
Reactivity Human, Mouse
Host Rabbit
Clonality Polyclonal
Isotype IgG
Calculated MW 14301 Da
Application Notes YPEL4 antibody can be used for detection of YPEL4 by Western blot at 1 µg/mL.
Additional Information
Gene ID 219539
Target/Specificity YPEL4;
Reconstitution & Storage YPEL4 antibody can be stored at 4℃ for three months and -20℃, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
PrecautionsYPEL4 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name YPEL4
Cellular Location Nucleus, nucleolus
Tissue Location Widely expressed. Detected adult brain, lung, colon, small intestine and ovary, and in fetal brain, lung, liver and spleen.
Citations (0)

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YPEL4 Antibody: YPEL4 (yippee-like 4) belongs to a family of five yippee-like proteins, all of which localize to the centrosome or mitotic spindle and are widely expressed in both adult and fetal tissue. This localization plus the fact that the family of human YPEL proteins share a high degree of sequence homology across species suggests that these proteins may have a conserved function involved in cell division. YPEL4 is ubiquitously expressed in adult tissues and has been shown to associate with the major vault protein (MVP). It has been suggested that MVP can inhibit YPEL4's ability to activate Elk-1 in the MAPK signaling pathway.


Hosono K, Sasaki T, Minoshima S, et al. Identification and characterization of a novel gene family YPEL in a wide spectrum of eukaryotic species. Gene 2004; 340: 31-43
Liang P, Wan Y, Yan Y, et al. MVP interacts with YPEL4 and inhibits YPEL4-mediated activities of the ERK signal pathway. Biochem. Cell. Biol. 2010; 88:445-50.

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$ 310.00
Cat# ASC11459
(40 western blots)
Availability: 5-7days
Bulk Size
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