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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   RLP2 Antibody   

RLP2 Antibody

  • WB - RLP2 Antibody ASC11469
    Western blot analysis of RLP2 in A549 cell lysate with RLP2 antibody at (A) 1 and (B) 2 µg/mL.
  • IHC - RLP2 Antibody ASC11469
    Immunohistochemistry of RLP2 in human lung tissue with RLP2 antibody at 2.5 µg/mL.
  • IF - RLP2 Antibody ASC11469
    Immunofluorescence of RLP2 in human lung tissue with RLP2 antibody at 20 µg/mL.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q969X0
Other Accession NP_659495, 21450828
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype IgG
Calculated MW 23986 Da
Application Notes RLP2 antibody can be used for detection of RLP2 by Western blot at 1 - 2 µg/mL. Antibody can also be used for immunohistochemistry starting at 2.5 µg/mL. For immunofluorescence start at 2.5 µg/mL.
Additional Information
Gene ID 196383
Target/Specificity RILPL2;
Reconstitution & Storage RLP2 antibody can be stored at 4℃ for three months and -20℃, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
PrecautionsRLP2 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Synonyms RLP2
Function Involved in cell shape and neuronal morphogenesis, positively regulating the establishment and maintenance of dendritic spines. Plays a role in cellular protein transport, including protein transport away from primary cilia. May function via activation of RAC1 and PAK1 (By similarity).
Cellular Location Cytoplasm, cytosol. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cell projection, cilium
Tissue Location Widely expressed. Expressed at higher level in lung.
Research Areas
Citations (0)

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RLP2 Antibody: The Rab interacting lysosomal protein-like 2 (RLP2) protein is related to the is lysosomal protein RILP which interacts with RAB7, a small GTPase that controls transport to endocytic degradative compartments. Little is known of the exact function of RLP2, but it is thought that RILP is a downstream effector of RAB7 and both proteins act together in the regulation of late endocytic traffic, suggesting that RLP2 may be involved in endocytic traffic with RILP or play a similar role. RILP and possible RLP2 may also play a role in the biogenesis of multivesicular bodies.


Wang T, Wong KK, and Hong W. A unique region of RILP distinguishes it from its related proteins in its regulation of lysosomal morphology and interaction with Rab7 and Rab34. Mol. Biol. Cell 2004; 15:815-26.
Cantalupo G, Alifano P, Roberti V, et al. Rab-interacting lysosomal protein (RILP): the Rab7 effector required for transport to lysosomes. EMBO J. 2001; 20:683-93.
Progida C, Spinosa MR, De Luca A, et al. RILP interacts with the VPS22 component of the ESCRT-II complex. Biochem. Biophys. Res. Commun. 2006; 347:1074-9.

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$ 310.00
Cat# ASC11469
(40 western blots)
Availability: 5-7days
Bulk Size
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